The State of the Art in Septoplasty: A Review of the Latest Achievements
Janipour M., Rezaei-Tazangi F.
Narrative Review, published in Biomed Res Int (2026) — summary generated from the PubMed abstract.
Evidence from laboratory and animal studies provides groundwork for understanding mechanisms and potential before human studies continue.
- Level A · Stronger Clinical Evidence
- Level B · Emerging clinical evidence with positive signals
- Level C · Early human research exploring benefits
- Level D · Scientific groundwork from lab and animal studies
- Emerging · Emerging topic under active research
This page is generated from the PubMed record. The Thai description is an automated summary of bibliographic fields and the abstract, not a full translation, and is not medical advice.
- Study type
- Narrative Review
- Journal
- Biomed Res Int (2026)
- Reported sample size
- —
- Source database
- Europe PMC
- PMID
- 41798689
- PMCID
- PMC12964075
- DOI
- 10.1155/bmri/7066464
Abstract (original English)
The deviated nasal septum is the most common cause of nasal airway obstruction, frequently diagnosed by otolaryngologists in clinical practice. Reports displayed that this condition affects 70%-80% of the population. The etiology of this upper airway problem is mainly related to intrinsic deformity or quadrangular cartilage dislocation from its bony borders, which can finally confer different disorders, such as breathing problems, sinus infections, snoring, headaches, exacerbating sleep apnea, and sleep disturbances. One of the most common methods for correcting a deviated nasal septum is septoplasty. However, this procedure still requires significant improvements to enhance its effectiveness and reduce the risk of surgery-related complications, particularly nasal septal perforation and the recurrence of deviation in adolescents and adults. In recent years, numerous strategies have been proposed to enhance septoplasty outcomes and reduce surgery-related complications. Many of these approaches focus on improving pain management, restoring olfactory function, alleviating symptoms, and enhancing clinical nasal outcomes. Additionally, they are aimed at promoting healing of the nasal mucosa and close septal perforations following surgery. This narrative review critically appraises the latest advancements in septoplasty, contrasting high-level evidence from large multicenter trials w
What this study does not prove
- • This study does not prove SVF is an approved treatment or a replacement for standard care.
- • This is a narrative review: it collects no new patient data and does not systematically appraise evidence quality.
Evidence level
Evidence from laboratory and animal studies provides groundwork for understanding mechanisms and potential before human studies continue.
How we grade evidenceBrowse all related research
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