Successful hair transplantation following repeated lipostructure in a case of morphea en coup de sabre : a multidisciplinary and regenerative approach.
Tesauro P., Tesauro P., Cremonesi I., Cornegliani G., Rivetti N., Muratori S.
Laboratory Study on Scar, Hair Loss, published in Dermatol Reports (2026) — summary generated from the PubMed abstract.
This page is generated from the PubMed record. The Thai description is an automated summary of bibliographic fields and the abstract, not a full translation, and is not medical advice.
- Study type
- Laboratory Study
- Journal
- Dermatol Reports (2026)
- Country
- Italy
- Reported sample size
- —
- PMID
- 40420729
- DOI
- 10.4081/dr.2025.10426
Abstract (original English)
We describe the successful combination of repeated autologous lipostructure and hair transplantation in a case of morphea en coup de sabre, highlighting the regenerative benefits of a multidisciplinary approach. A 40-year-old woman with long-standing, stable frontoparietal and frontotemporal atrophy and alopecia underwent four fat grafting sessions using the Coleman technique over 5 years. Nine months after the final procedure, she received follicular unit extraction (FUE) hair transplantation with 1,600 grafts. The postoperative course was uneventful, with rapid and stable regrowth observed from the third month. At 12 months, the aesthetic outcome was excellent, with nearly complete graft survival and high patient satisfaction. This is the first reported case of FUE transplantation following multiple lipostructure sessions in morphea en coup de sabre. Fat grafting may enhance graft take by improving dermal quality and vascularization. This combined approach offers a promising solution for scarring alopecia in selected, stable patients.
What this study does not prove
- • This study does not prove SVF is an approved treatment or a replacement for standard care.
- • This is preclinical work; animal or laboratory results cannot be applied to humans.
Evidence level
Evidence comes from animal or laboratory studies and has not been confirmed in humans.
How we grade evidenceRelated research
- Level ASystematic Review
Regenerative Medicine for Atrophic Scars: A Systematic Review of Extracellular Vesicles, Conditioned Media, Stromal Vascular Fraction, and Mesenchymal Stem Cells.
Systematic Review with a reported sample of 177 on Chronic Wound, Scar, published in Aesthetic Plast Surg (2026) — summary generated from the PubMed abstract.
- 2026
- n = 177
Aesthetic Plast Surg - Level ASystematic Review
Clinical Applications of Autologous Fat Grafting in Pathological Hand Conditions.
Systematic Review with a reported sample of 7 on Osteoarthritis, Scar, published in J Hand Surg Asian Pac Vol (2026) — summary generated from the PubMed abstract.
- 2026
- n = 7
J Hand Surg Asian Pac Vol - Level AMeta-analysis
Stem cell therapy in thin endometrium and Asherman's syndrome: a systematic review and meta-analysis.
Meta-analysis with a reported sample of 323 on Scar, published in Eur J Obstet Gynecol Reprod Biol (2026) — summary generated from the PubMed abstract.
- 2026
- n = 323
Eur J Obstet Gynecol Reprod Biol - Level ASystematic Review
Efficacy and safety of autologous cell-based therapies for atrophic acne scar treatment: an updated systematic review and meta-analysis with in-depth methodological and clinical insights.
Systematic Review with a reported sample of 500 on Chronic Wound, Scar, published in Front Cell Dev Biol (2026) — summary generated from the PubMed abstract.
- 2026
- n = 500
Front Cell Dev Biol - Level ASystematic Review
Injectable Fillers for Atrophic Acne Scars: A Systematic Review of Mechanisms, Evidence, and Clinical Algorithms.
Systematic Review on Scar, published in Clin Cosmet Investig Dermatol (2026) — summary generated from the PubMed abstract.
- 2026
Clin Cosmet Investig Dermatol - Level ASystematic Review
Adipose-Derived Stem Cells as Therapeutic Approach in Hypertrophic Scar Formation-A Systematic Review.
Systematic Review on Chronic Wound, Scar, Immune Modulation, published in Int Wound J (2026) — summary generated from the PubMed abstract.
- 2026
Int Wound J