Level C· Early human research exploring benefitsProspective StudyPubMedOpen access

Successful hair transplantation following repeated lipostructure in a case of morphea en coup de sabre : a multidisciplinary and regenerative approach.

Tesauro P., Tesauro P., Cremonesi I., Cornegliani G., Rivetti N., Muratori S.

Prospective Study on Scar, Hair Loss, published in Dermatol Reports (2025) — summary generated from the PubMed abstract.

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Level C· Early human research exploring benefitsEvidence level of this study

Early human evidence such as case series or small samples is exploring possible benefits.

  • Level A · Stronger Clinical Evidence
  • Level B · Emerging clinical evidence with positive signals
  • Level C · Early human research exploring benefits
  • Level D · Scientific groundwork from lab and animal studies
  • Emerging · Emerging topic under active research
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This page is generated from the PubMed record. The Thai description is an automated summary of bibliographic fields and the abstract, not a full translation, and is not medical advice.

Study type
Prospective Study
Journal
Dermatol Reports (2025)
Country
Italy
Reported sample size
—
Source database
PubMed
PMID
40420729
PMCID
PMC12990048
DOI
10.4081/dr.2025.10426

Abstract (original English)

We describe the successful combination of repeated autologous lipostructure and hair transplantation in a case of morphea en coup de sabre, highlighting the regenerative benefits of a multidisciplinary approach. A 40-year-old woman with long-standing, stable frontoparietal and frontotemporal atrophy and alopecia underwent four fat grafting sessions using the Coleman technique over 5 years. Nine months after the final procedure, she received follicular unit extraction (FUE) hair transplantation with 1,600 grafts. The postoperative course was uneventful, with rapid and stable regrowth observed from the third month. At 12 months, the aesthetic outcome was excellent, with nearly complete graft survival and high patient satisfaction. This is the first reported case of FUE transplantation following multiple lipostructure sessions in morphea en coup de sabre. Fat grafting may enhance graft take by improving dermal quality and vascularization. This combined approach offers a promising solution for scarring alopecia in selected, stable patients.

What this study does not prove

  • • This study does not prove SVF is an approved treatment or a replacement for standard care.

Evidence level

Early human evidence such as case series or small samples is exploring possible benefits.

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