Successful hair transplantation following repeated lipostructure in a case of morphea en coup de sabre : a multidisciplinary and regenerative approach.
Tesauro P., Tesauro P., Cremonesi I., Cornegliani G., Rivetti N., Muratori S.
Prospective Study on Scar, Hair Loss, published in Dermatol Reports (2025) — summary generated from the PubMed abstract.
Early human evidence such as case series or small samples is exploring possible benefits.
- Level A · Stronger Clinical Evidence
- Level B · Emerging clinical evidence with positive signals
- Level C · Early human research exploring benefits
- Level D · Scientific groundwork from lab and animal studies
- Emerging · Emerging topic under active research
This page is generated from the PubMed record. The Thai description is an automated summary of bibliographic fields and the abstract, not a full translation, and is not medical advice.
- Study type
- Prospective Study
- Journal
- Dermatol Reports (2025)
- Country
- Italy
- Reported sample size
- —
- Source database
- PubMed
- PMID
- 40420729
- PMCID
- PMC12990048
- DOI
- 10.4081/dr.2025.10426
Abstract (original English)
We describe the successful combination of repeated autologous lipostructure and hair transplantation in a case of morphea en coup de sabre, highlighting the regenerative benefits of a multidisciplinary approach. A 40-year-old woman with long-standing, stable frontoparietal and frontotemporal atrophy and alopecia underwent four fat grafting sessions using the Coleman technique over 5 years. Nine months after the final procedure, she received follicular unit extraction (FUE) hair transplantation with 1,600 grafts. The postoperative course was uneventful, with rapid and stable regrowth observed from the third month. At 12 months, the aesthetic outcome was excellent, with nearly complete graft survival and high patient satisfaction. This is the first reported case of FUE transplantation following multiple lipostructure sessions in morphea en coup de sabre. Fat grafting may enhance graft take by improving dermal quality and vascularization. This combined approach offers a promising solution for scarring alopecia in selected, stable patients.
What this study does not prove
- • This study does not prove SVF is an approved treatment or a replacement for standard care.
Evidence level
Early human evidence such as case series or small samples is exploring possible benefits.
How we grade evidenceBrowse all related research
Filter the research library by this study's title keywords, author, or publication year.
Related research
- Level ASystematic ReviewPubMed
Clinical Applications of Autologous Fat Grafting in Pathological Hand Conditions.
Systematic Review with a reported sample of 7 on Osteoarthritis, Scar, published in J Hand Surg Asian Pac Vol (2026) — summary generated from the PubMed abstract.
- 2026
- n = 7
J Hand Surg Asian Pac Vol - Level AMeta-analysisPubMed
Stem cell therapy in thin endometrium and Asherman's syndrome: a systematic review and meta-analysis.
Meta-analysis with a reported sample of 323 on Scar, published in Eur J Obstet Gynecol Reprod Biol (2026) — summary generated from the PubMed abstract.
- 2026
- n = 323
Eur J Obstet Gynecol Reprod Biol - Level AMeta-analysisEurope PMC
Therapeutic value of mesenchymal stem cell-derived extracellular vesicles in hypertrophic and keloid scars: a systematic review and meta-analysis
Meta-analysis on Chronic Wound, Scar, published in Front Cell Dev Biol (2026) — summary generated from the PubMed abstract.
- 2026
Front Cell Dev Biol - Level AMeta-analysisPubMed
Efficacy and safety of autologous cell-based therapies for atrophic acne scar treatment: an updated systematic review and meta-analysis with in-depth methodological and clinical insights.
Meta-analysis with a reported sample of 500 on Chronic Wound, Scar, published in Front Cell Dev Biol (2026) — summary generated from the PubMed abstract.
- 2026
- n = 500
Front Cell Dev Biol - Level ASystematic ReviewEurope PMC
Comparative Efficacy and Safety of Fractional CO<sub>2</sub> Laser and Gold Microneedling Radiofrequency for Atrophic Acne Scars: A Systematic Review
Systematic Review on Chronic Wound, Scar, published in Skin Res Technol (2026) — summary generated from the PubMed abstract.
- 2026
Skin Res Technol - Level AMeta-analysisPubMed
Role of exosome therapy in reconstructive surgery: a review.
Meta-analysis on Chronic Wound, Scar, Immune Modulation, published in Front Med (Lausanne) (2026) — summary generated from the PubMed abstract.
- 2026
Front Med (Lausanne)1 citations