Level C· Early human research exploring benefitsProspective StudyPubMed

Surgical correction of progressive hemifacial atrophy with onlay bone graft combined with soft tissue augmentation.

Myung Y., Lee YH., Chang H.

Prospective Study with a reported sample of 10 on Face & Skin, published in J Craniofac Surg (2012) — summary generated from the PubMed abstract.

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Level C· Early human research exploring benefitsEvidence level of this study

Early human evidence such as case series or small samples is exploring possible benefits.

  • Level A · Stronger Clinical Evidence
  • Level B · Emerging clinical evidence with positive signals
  • Level C · Early human research exploring benefits
  • Level D · Scientific groundwork from lab and animal studies
  • Emerging · Emerging topic under active research
Read the A–D evidence level guide

This page is generated from the PubMed record. The Thai description is an automated summary of bibliographic fields and the abstract, not a full translation, and is not medical advice.

Study type
Prospective Study
Journal
J Craniofac Surg (2012)
Country
United States
Reported sample size
10
Source database
PubMed
PMID
23147307
DOI
10.1097/SCS.0b013e318264b0ab

Abstract (original English)

Moderate-to-severe Parry-Romberg syndrome involves progressive atrophy of facial bony structures as well as changes in skin and subcutaneous tissue. To correct facial asymmetry in PRS patients, it is important to restore facial bony alignment and obtain a symmetrical appearance. The authors propose a new combination method of onlay bone grafting and adipofascial free flap. Applying this technique, we performed rib bone graft with concomitant free flap transfer in 10 patients. All patients showed moderate-to-severe findings of PRS, involving skull deformity. Both male and female were 4 and 6 patients each, and the age of the patients at which they received surgery ranged from 10 to 52 years, with an average of 24.8 years of age. During the follow-up period, ancillary procedures including dermofat graft and hyaluronic acid filler injections were performed to achieve fine facial contour and facial symmetry. There were no severe complications such as infection or postoperative bleeding. All patients were satisfied with the result, and postoperative CT scanning revealed successful uptake of grafted bone. Onlay frame bone graft by using rib bone as donor material, with combination of facial fat free flap transfer can be an excellent choice in restoring facial symmetry in severe cases of progressive hemifacial atrophy.

What this study does not prove

  • • This study does not prove SVF is an approved treatment or a replacement for standard care.

Evidence level

Early human evidence such as case series or small samples is exploring possible benefits.

How we grade evidence
Adipose TissueAdolescentAdultBone TransplantationChildFacial HemiatrophyFasciaFemaleFree Tissue FlapsHumans

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