Surgical nerve wrapping for brachial plexus neuropathy: A systematic review
Thuau F., Gadbled G., Lahmar T., Perrot P., Lancien U.
Systematic Review with a reported sample of 214, published in JPRAS Open (2026) — summary generated from the PubMed abstract.
Relatively higher-quality human studies compared with other topics in this database, e.g. multiple RCTs or systematic reviews. This does not mean it is standard or approved care.
- Level A · Stronger Clinical Evidence
- Level B · Emerging clinical evidence with positive signals
- Level C · Early human research exploring benefits
- Level D · Scientific groundwork from lab and animal studies
- Emerging · Emerging topic under active research
This page is generated from the PubMed record. The Thai description is an automated summary of bibliographic fields and the abstract, not a full translation, and is not medical advice.
- Study type
- Systematic Review
- Journal
- JPRAS Open (2026)
- Reported sample size
- 214
- Source database
- Europe PMC
- PMID
- 41438880
- PMCID
- PMC12719742
- DOI
- 10.1016/j.jpra.2025.11.005
- Citations
- 1
Abstract (original English)
Introduction Nerve wrapping provides protection, reduces adhesions, and supports regeneration, with proven benefits in median and ulnar neuropathies. Brachial plexus neuropathies-arising from neurogenic thoracic outlet syndrome (NTOS), radiation-induced brachial plexopathy (RIBP), or trauma-pose distinct challenges, and indications for wrapping remain poorly defined. We conducted a systematic review of brachial plexus wrapping techniques to clarify approaches and outcomes. Methods PubMed, Scopus, Cochrane Library, and ProQuest were searched following PRISMA guidelines; the protocol was registered on PROSPERO. Risk of bias was assessed with the MINORS tool. Extracted data included patient characteristics, surgical techniques, functional outcomes, complications, and recurrences. Results Seventeen studies involving 645 patients (mean age 43.8 years; M/F 1/3.92) were included. The main indications were NTOS (77.1 %) and RIBP (22.6 %). Eleven wrapping techniques were identified: eight different flaps ( n = 214) from omental, muscular, or adipofascial origins, and three medical devices ( n = 426). NTOS was mainly treated with synthetic membranes, and RIBP with flaps. Pain reduction was reported in 91.9 % of cases, with complete relief in 62.8 %. For RIBP, motor improvement (52.5 %) and sensory improvement (50 %) were observed, while QuickDASH scores for NTOS improved by a mean of 23.
What this study does not prove
- • This study does not prove SVF is an approved treatment or a replacement for standard care.
Evidence level
Relatively higher-quality human studies compared with other topics in this database, e.g. multiple RCTs or systematic reviews. This does not mean it is standard or approved care.
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