Level B· Emerging clinical evidence with positive signalsRandomized Controlled TrialPubMedOpen access

Synergistic Effects of Endolift With Complementary Cosmetic Procedures: A Narrative Review and Comprehensive Approach.

Nilforoushzadeh MA., Savoji PB., Fakhim T., Rafiei S., Mirbahari SN.

Randomized Controlled Trial on Skin Aging, published in J Cosmet Dermatol (2026) — summary generated from the PubMed abstract.

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Level B· Emerging clinical evidence with positive signalsEvidence level of this study

Several human studies show positive signals, while research methods and sample sizes continue to develop.

  • Level A · Stronger Clinical Evidence
  • Level B · Emerging clinical evidence with positive signals
  • Level C · Early human research exploring benefits
  • Level D · Scientific groundwork from lab and animal studies
  • Emerging · Emerging topic under active research
Read the A–D evidence level guide

This page is generated from the PubMed record. The Thai description is an automated summary of bibliographic fields and the abstract, not a full translation, and is not medical advice.

Study type
Randomized Controlled Trial
Journal
J Cosmet Dermatol (2026)
Country
England
Reported sample size
—
Source database
PubMed
PMID
42153325
PMCID
PMC13184809
DOI
10.1111/jocd.70922
Citations
1

Abstract (original English)

Background The landscape of aesthetic medicine has increasingly favored minimally invasive interventions, with the 1470 nm diode laser (Endolift) gaining prominence as a viable alternative to surgical lifting for soft-tissue remodeling and lipolysis. Aims This narrative review synthesizes current evidence on the mechanism, clinical versatility, and safety profile of Endolift. A primary objective is to evaluate the synergistic potential of combining this technology with complementary aesthetic modalities to optimize patient outcomes. Patients/methods A comprehensive search of PubMed/MEDLINE, Scopus, and Google Scholar was conducted. We analyzed key literature on the 1470 nm diode laser, selecting studies that document its efficacy as monotherapy and in combination with injectables or regenerative techniques. Results The 1470 nm wavelength exhibits high affinity for water, facilitating selective lipolysis and stimulating deep collagen restructuring through controlled photothermal interaction. Clinical findings consistently report tangible improvements in skin laxity and contouring with limited recovery time. Notably, multimodal protocols-integrating dermal fillers, nanofat, or surface resurfacing-appear to enhance aesthetic outcomes by simultaneously addressing volume deficits and superficial texture alongside tissue tightening. Conclusions Endolift represents a robust, minimally

What this study does not prove

  • • This study does not prove SVF is an approved treatment or a replacement for standard care.

Evidence level

Several human studies show positive signals, while research methods and sample sizes continue to develop.

How we grade evidence
HumansCosmetic TechniquesCombined Modality TherapySkin AgingDermal FillersLasers, SemiconductorRejuvenationEsthetics

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