Level D· Scientific groundwork from lab and animal studiesNarrative ReviewEurope PMC

[Tetrahedral Framework Nucleic Acids and Human Health]

Lin YF.

Narrative Review, published in Sichuan Da Xue Xue Bao Yi Xue Ban (2021) — summary generated from the PubMed abstract.

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Level D· Scientific groundwork from lab and animal studiesEvidence level of this study

Evidence from laboratory and animal studies provides groundwork for understanding mechanisms and potential before human studies continue.

  • Level A · Stronger Clinical Evidence
  • Level B · Emerging clinical evidence with positive signals
  • Level C · Early human research exploring benefits
  • Level D · Scientific groundwork from lab and animal studies
  • Emerging · Emerging topic under active research
Read the A–D evidence level guide

This page is generated from the PubMed record. The Thai description is an automated summary of bibliographic fields and the abstract, not a full translation, and is not medical advice.

Study type
Narrative Review
Journal
Sichuan Da Xue Xue Bao Yi Xue Ban (2021)
Reported sample size
—
Source database
Europe PMC
PMID
34018349
PMCID
PMC10409210
DOI
10.12182/20210560301
Citations
1

Abstract (original English)

In recent years, tetrahedral framework nucleic acids (tFNAs) have become a hot topic in the field of DNA nanomaterials due to their excellent mechanical, chemical and biological properties. By taking advantage of these merits, tFNAs of varied sizes and modification methods have been designed and applied in diverse fields such as regenerative medicine, biosensors, and tumor treatment to promote human health. This paper reviews the current research progress of tFNAs in human health-related fields, and the future challenges in the clinical applications of tFNAs.

What this study does not prove

  • • This study does not prove SVF is an approved treatment or a replacement for standard care.
  • • This is a narrative review: it collects no new patient data and does not systematically appraise evidence quality.

Evidence level

Evidence from laboratory and animal studies provides groundwork for understanding mechanisms and potential before human studies continue.

How we grade evidence
HumansNucleic AcidsDNANanostructures

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