Level D· Scientific groundwork from lab and animal studiesNarrative ReviewPubMedOpen access

Therapeutic potential of adipose tissue in aesthetic medicine.

Choudhery MS., Arif T., Afzal A., Mahmood R.

Narrative Review on Face & Skin, published in World J Exp Med (2025) — summary generated from the PubMed abstract.

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Level D· Scientific groundwork from lab and animal studiesEvidence level of this study

Evidence from laboratory and animal studies provides groundwork for understanding mechanisms and potential before human studies continue.

  • Level A · Stronger Clinical Evidence
  • Level B · Emerging clinical evidence with positive signals
  • Level C · Early human research exploring benefits
  • Level D · Scientific groundwork from lab and animal studies
  • Emerging · Emerging topic under active research
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This page is generated from the PubMed record. The Thai description is an automated summary of bibliographic fields and the abstract, not a full translation, and is not medical advice.

Study type
Narrative Review
Journal
World J Exp Med (2025)
Country
United States
Reported sample size
—
Source database
PubMed
PMID
41523767
PMCID
PMC12781629
DOI
10.5493/wjem.v15.i3.106641

Abstract (original English)

Aesthetic medicine is a branch of medicine dedicated to improve an individual's appearance and overall visual appeal. Conventional aesthetic treatments have limitations, including the risk of complications, allergic reactions, and temporary benefits. Adipose tissue offers a promising alternative to conventional aesthetic treatments. The regenerative properties, accessibility and versatility of adipose tissue make it an attractive option for individuals seeking natural and long-lasting aesthetic results. Adipose tissue is rich source of adipose tissue derived stem cells (ASCs), growth factors and extracellular matrix. It can restore and rejuvenate the damaged and aged tissues. Adipose tissue can be used in different formats such as pure adipose tissue grafts, stromal vascular fraction, nanofat, macrofat, microfat and as a pure population of ASCs. In addition, ASC derived exosomes offer a unique cell-free therapy advantages bioactive molecules like growth factors, cytokines, and microRNAs to stimulate collagen production, improve skin texture, and address pigmentation issues. This review highlights the multifaceted potential of adipose tissue in aesthetic medicine. It discusses its diverse applications, the biological mechanisms involved, and emerging therapeutic approaches. Moreover, this review also highlights the challenges and future direction of using adipose tissue-based th

What this study does not prove

  • • This study does not prove SVF is an approved treatment or a replacement for standard care.
  • • This is a narrative review: it collects no new patient data and does not systematically appraise evidence quality.

Evidence level

Evidence from laboratory and animal studies provides groundwork for understanding mechanisms and potential before human studies continue.

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