Level D· Scientific groundwork from lab and animal studiesNarrative ReviewPubMed

Tissue-Engineered Autologous Breast Regeneration with Brava®-Assisted Fat Grafting.

Kosowski TR., Rigotti G., Khouri RK.

Narrative Review with a reported sample of 488, published in Clin Plast Surg (2015) — summary generated from the PubMed abstract.

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Level D· Scientific groundwork from lab and animal studiesEvidence level of this study

Evidence from laboratory and animal studies provides groundwork for understanding mechanisms and potential before human studies continue.

  • Level A · Stronger Clinical Evidence
  • Level B · Emerging clinical evidence with positive signals
  • Level C · Early human research exploring benefits
  • Level D · Scientific groundwork from lab and animal studies
  • Emerging · Emerging topic under active research
Read the A–D evidence level guide

This page is generated from the PubMed record. The Thai description is an automated summary of bibliographic fields and the abstract, not a full translation, and is not medical advice.

Study type
Narrative Review
Journal
Clin Plast Surg (2015)
Country
United States
Reported sample size
488
Source database
PubMed
PMID
26116938
DOI
10.1016/j.cps.2015.03.001
Citations
32

Abstract (original English)

A technique of whole and partial breast reconstruction is described based on tissue-engineering principles. Brava-assisted external tissue expansion generates an in situ biological recipient scaffold that favors the survival of large volumes of autologous fat graft required for breast reconstruction. Also presented are the results of the authors' multicenter experience with this regenerative alternative in 488 patients over a 7-year period tracking surgical complications, patient satisfaction, efficacy, and costs.

What this study does not prove

  • • This study does not prove SVF is an approved treatment or a replacement for standard care.
  • • This is a narrative review: it collects no new patient data and does not systematically appraise evidence quality.

Evidence level

Evidence from laboratory and animal studies provides groundwork for understanding mechanisms and potential before human studies continue.

How we grade evidence
Adipose TissueBreastBreast NeoplasmsFemaleHumansLipectomyMammaplastyMastectomyRegenerationTissue Engineering

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