Level D· Scientific groundwork from lab and animal studiesLaboratory StudyEurope PMC

Tissue-Specific and Genetic Regulation of Insulin Sensitivity-Associated Transcripts in African Americans

Sharma NK., Sajuthi SP., Chou JW., Calles-Escandon J., Demons J., Rogers S.

Laboratory Study on Type 2 Diabetes, published in J Clin Endocrinol Metab (2016) — summary generated from the PubMed abstract.

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Level D· Scientific groundwork from lab and animal studiesEvidence level of this study

Evidence from laboratory and animal studies provides groundwork for understanding mechanisms and potential before human studies continue.

  • Level A · Stronger Clinical Evidence
  • Level B · Emerging clinical evidence with positive signals
  • Level C · Early human research exploring benefits
  • Level D · Scientific groundwork from lab and animal studies
  • Emerging · Emerging topic under active research
Read the A–D evidence level guide

This page is generated from the PubMed record. The Thai description is an automated summary of bibliographic fields and the abstract, not a full translation, and is not medical advice.

Study type
Laboratory Study
Journal
J Clin Endocrinol Metab (2016)
Reported sample size
—
Source database
Europe PMC
PMID
26789776
PMCID
PMC4880154
DOI
10.1210/jc.2015-3336
Citations
34

Abstract (original English)

Integrative multiomics analyses of adipose and muscle tissue transcripts, S, and genotypes revealed novel genetic regulatory mechanisms of insulin resistance in African Americans.

What this study does not prove

  • • This study does not prove SVF is an approved treatment or a replacement for standard care.
  • • This is preclinical work; animal or laboratory results cannot be applied to humans.

Evidence level

Evidence from laboratory and animal studies provides groundwork for understanding mechanisms and potential before human studies continue.

How we grade evidence
Muscle, SkeletalAdipose TissueHumansInsulin ResistanceGlucose Tolerance TestCross-Sectional StudiesGene Expression RegulationAdolescentAdultMiddle Aged

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