Level D· Scientific groundwork from lab and animal studiesAnimal StudyPubMed

Transduction Function of a Magnetic Nanoparticle TMADM for Stem-Cell Imaging with Quantum Dots.

Ogihara Y., Yukawa H., Onoshima D., Baba Y.

Animal Study, published in Anal Sci (2017) — summary generated from the PubMed abstract.

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Level D· Scientific groundwork from lab and animal studiesEvidence level of this study

Evidence from laboratory and animal studies provides groundwork for understanding mechanisms and potential before human studies continue.

  • Level A · Stronger Clinical Evidence
  • Level B · Emerging clinical evidence with positive signals
  • Level C · Early human research exploring benefits
  • Level D · Scientific groundwork from lab and animal studies
  • Emerging · Emerging topic under active research
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This page is generated from the PubMed record. The Thai description is an automated summary of bibliographic fields and the abstract, not a full translation, and is not medical advice.

Study type
Animal Study
Journal
Anal Sci (2017)
Country
Switzerland
Reported sample size
—
Source database
PubMed
PMID
28190831
DOI
10.2116/analsci.33.143
Citations
5

Abstract (original English)

We investigated the transduction function of a cationic dextran hydroxypropyltrimethyl ammonium chloride-coated magnetic iron oxide nanoparticle (TMADM-03) for transducing quantum dots (QDs) into adipose tissue-derived stem cells (ASCs). As a result, the fluorescence intensity of ASCs labeled with QDs using TMADM-03 was much higher than that of QDs only labeling. These data suggest that TMADM-03 can be useful as a transduction agent for QDs in stem-cell imaging.

What this study does not prove

  • • This study does not prove SVF is an approved treatment or a replacement for standard care.
  • • This is preclinical work; animal or laboratory results cannot be applied to humans.

Evidence level

Evidence from laboratory and animal studies provides groundwork for understanding mechanisms and potential before human studies continue.

How we grade evidence
Adipose TissueAnimalsDextransFemaleFerric CompoundsMetal NanoparticlesMiceMolecular ImagingOptical ImagingPropanols

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