Level C· Early human research exploring benefitsRetrospective StudyEurope PMCOpen access

Ultrasound-Guided Female Equilibrated Minimal Muscularization and Enhancement (U-Femme)

Proto R., Hoyos AE., Perez Pachon ME., Oñate-Valdivieso C., Oñate-Valdivieso D., Duarte P.

Retrospective Study on Face & Skin, Back & Spine, published in Aesthet Surg J Open Forum (2025) — summary generated from the PubMed abstract.

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Level C· Early human research exploring benefitsEvidence level of this study

Early human evidence such as case series or small samples is exploring possible benefits.

  • Level A · Stronger Clinical Evidence
  • Level B · Emerging clinical evidence with positive signals
  • Level C · Early human research exploring benefits
  • Level D · Scientific groundwork from lab and animal studies
  • Emerging · Emerging topic under active research
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This page is generated from the PubMed record. The Thai description is an automated summary of bibliographic fields and the abstract, not a full translation, and is not medical advice.

Study type
Retrospective Study
Journal
Aesthet Surg J Open Forum (2025)
Reported sample size
—
Source database
Europe PMC
PMID
40236882
PMCID
PMC11997775
DOI
10.1093/asjof/ojae103

Abstract (original English)

Background High-definition liposculpture (HDL) has undergone significant evolution since its initial description, with the goal of achieving more natural outcomes and a muscular-defined appearance. The introduction of intramuscular fat grafting has enhanced contouring capabilities, with its applications extending to various muscle groups. Subperiosteal fat grafting efficacy and safety are well-established in facial surgery. Objectives Describe the technique of combining ultrasound (US)-guided subperiosteal lipoinjection of the anterior superior iliac spine (bikini bridge) plus intramuscular fat grafting of the internal oblique muscles with HDL. Methods A retrospective cohort study was conducted across different specialized plastic surgery centers. Adult patients who underwent bikini bridge and dynamic definition liposculpture were included. All patients were informed of the innovative use of the technique and consented to participate. Descriptive statistical analysis was performed to summarize the variables. Results A total of 105 consecutive patients were included for analysis. Patients were mostly females (86.7%) plus 14 male patients (13.3%) who were in the gender reassignment process. Mean age was 34.3 years (standard deviation [SD] 8.7 years) and the median BMI was 22.9 kg/m 2 (SD 2.74 kg/m 2 ). All patients underwent fat grafting the iliac spines + the oblique muscles as

What this study does not prove

  • • This study does not prove SVF is an approved treatment or a replacement for standard care.
  • • Without an adequate control group, treatment effects cannot be separated from other factors.

Evidence level

Early human evidence such as case series or small samples is exploring possible benefits.

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