Level D· Scientific groundwork from lab and animal studiesNarrative ReviewEurope PMCOpen access

Umbilical cord tissue cryopreservation: a short review

Arutyunyan I., Fatkhudinov T., Sukhikh G.

Narrative Review, published in Stem Cell Res Ther (2018) — summary generated from the PubMed abstract.

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Level D· Scientific groundwork from lab and animal studiesEvidence level of this study

Evidence from laboratory and animal studies provides groundwork for understanding mechanisms and potential before human studies continue.

  • Level A · Stronger Clinical Evidence
  • Level B · Emerging clinical evidence with positive signals
  • Level C · Early human research exploring benefits
  • Level D · Scientific groundwork from lab and animal studies
  • Emerging · Emerging topic under active research
Read the A–D evidence level guide

This page is generated from the PubMed record. The Thai description is an automated summary of bibliographic fields and the abstract, not a full translation, and is not medical advice.

Study type
Narrative Review
Journal
Stem Cell Res Ther (2018)
Reported sample size
—
Source database
Europe PMC
PMID
30219095
PMCID
PMC6138889
DOI
10.1186/s13287-018-0992-0
Citations
42

Abstract (original English)

In this review we present current evidence on the possibility of umbilical cord tissue cryopreservation for subsequent clinical use. Protocols for obtaining umbilical cord-derived vessels, Wharton's jelly-based grafts, multipotent stromal cells, and other biomedical products from cryopreserved umbilical cords are highlighted, and their prospective clinical applications are discussed. Examination of recent literature indicates we should expect high demand for cryopreservation of umbilical cord tissues in the near future.

What this study does not prove

  • • This study does not prove SVF is an approved treatment or a replacement for standard care.
  • • This is a narrative review: it collects no new patient data and does not systematically appraise evidence quality.

Evidence level

Evidence from laboratory and animal studies provides groundwork for understanding mechanisms and potential before human studies continue.

How we grade evidence
Mesenchymal Stem CellsFetal BloodUmbilical CordHumansGlycerolDimethyl SulfoxideCryoprotective AgentsCryopreservationBlood Vessel ProsthesisCell Differentiation

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