Utilization of animal by-products as sources of bioactive compounds and FBS alternatives for cultured meat: a comprehensive review
Lee J., Lee DY., Mariano EJ., Park JW., Namkung S., Choi SY.
Narrative Review, published in Food Sci Anim Resour (2026) — summary generated from the PubMed abstract.
Evidence from laboratory and animal studies provides groundwork for understanding mechanisms and potential before human studies continue.
- Level A · Stronger Clinical Evidence
- Level B · Emerging clinical evidence with positive signals
- Level C · Early human research exploring benefits
- Level D · Scientific groundwork from lab and animal studies
- Emerging · Emerging topic under active research
This page is generated from the PubMed record. The Thai description is an automated summary of bibliographic fields and the abstract, not a full translation, and is not medical advice.
- Study type
- Narrative Review
- Journal
- Food Sci Anim Resour (2026)
- Reported sample size
- —
- Source database
- Europe PMC
- PMID
- 41848817
- PMCID
- PMC12995063
- DOI
- 10.1007/s44463-025-00035-8
- Citations
- 1
Abstract (original English)
Slaughterhouse by-products have been widely utilized in food, pharmaceutical, and biomaterial applications across Asia, Europe, and the Americas. This review examines current research on enhancing the value and utilization of these by-products, with a particular focus on their potential as alternatives to fetal bovine serum (FBS), a critical component of cell culture media. Among these, livestock and poultry blood-produced at over 30 million tons annually-is of particular interest; however, only approximately 30% is currently used in food products or additives. Recent studies suggest that serum derived from bovine, porcine, and chicken blood may serve as viable substitutes for FBS. Recent studies have suggested that serum derived from adult bovine, porcine, and chicken blood may partially substitute for FBS, with replacement efficiencies reported to reach up to approximately 80%, depending on the species. Inedible by-products, including feathers, bones, leather, and hooves, are primarily processed into fertilizers and animal feed due to their high protein and mineral content. Despite the considerable volume of slaughter by-products generated, their application in cell culture systems and other high-value industries remains underdeveloped. Promoting the industrial utilization of these materials could not only improve resource efficiency and reduce environmental impact but also c
What this study does not prove
- • This study does not prove SVF is an approved treatment or a replacement for standard care.
- • This is a narrative review: it collects no new patient data and does not systematically appraise evidence quality.
Evidence level
Evidence from laboratory and animal studies provides groundwork for understanding mechanisms and potential before human studies continue.
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