Visualized trends and bibliometric analysis in ankle cartilage repair from 2004 to 2024
Fu X., Zhang Z., Wang Y., Lu L., Chen T., Deng H.
Systematic Review on Cartilage Damage, Ankle Injury, published in Front Med (Lausanne) (2024) — summary generated from the PubMed abstract.
Relatively higher-quality human studies compared with other topics in this database, e.g. multiple RCTs or systematic reviews. This does not mean it is standard or approved care.
- Level A · Stronger Clinical Evidence
- Level B · Emerging clinical evidence with positive signals
- Level C · Early human research exploring benefits
- Level D · Scientific groundwork from lab and animal studies
- Emerging · Emerging topic under active research
This page is generated from the PubMed record. The Thai description is an automated summary of bibliographic fields and the abstract, not a full translation, and is not medical advice.
- Study type
- Systematic Review
- Journal
- Front Med (Lausanne) (2024)
- Reported sample size
- —
- Source database
- Europe PMC
- PMID
- 39635584
- PMCID
- PMC11614622
- DOI
- 10.3389/fmed.2024.1503707
Abstract (original English)
Ankle cartilage injuries are a common sports-related condition that significantly impairs patients' daily activities and imposes substantial economic burdens on both families and society. Effective cartilage repair strategies are crucial to addressing this pathological condition. Current conservative treatments include muscle strengthening, use of ankle braces, physical therapy, and the administration of NSAIDs. In cases of severe injury, surgical interventions such as osteophyte resection and cartilage transplantation may be necessary. However, the inherent regenerative capacity of articular cartilage is limited, and conventional treatments are insufficient to promote cartilage regeneration and repair. Consequently, innovative therapies such as stem cell therapy, exosome therapy, and cartilage regeneration scaffolds are prioritized for future development. In recent years, significant progress has been made in ankle cartilage repair. While bibliometric studies on cartilage repair exist, specific analyses focused on ankle cartilage repair are lacking. This study aims to address this gap by conducting a bibliometric analysis of 131 articles published over the past two decades, highlighting development trajectories, research hotspots, and evolutionary trends through knowledge mapping. Our findings indicate growing global interest, with the United States leading in international co
What this study does not prove
- • This study does not prove SVF is an approved treatment or a replacement for standard care.
Evidence level
Relatively higher-quality human studies compared with other topics in this database, e.g. multiple RCTs or systematic reviews. This does not mean it is standard or approved care.
How we grade evidenceBrowse all related research
Filter the research library by this study's title keywords, author, or publication year.
Related research
- Level ASystematic ReviewPubMed
A Systematic Review on Amnion as a Cell Delivery Scaffolding Material for Cartilage Regeneration in Pre-Clinical and Clinical Studies.
Systematic Review on Osteoarthritis, Cartilage Damage, published in Bioengineering (Basel) (2026) — summary generated from the PubMed abstract.
- 2026
Bioengineering (Basel)1 citations - Level ASystematic ReviewPubMed
Intra-articular adipose-derived cell therapies for knee osteoarthritis: a systematic review of randomized controlled trials.
Systematic Review on Knee Osteoarthritis, Osteoarthritis, Cartilage Damage, published in Front Med (Lausanne) (2026) — summary generated from the PubMed abstract.
- 2026
Front Med (Lausanne) - Level ASystematic ReviewEurope PMC
Subchondral Knee Injections: A Comprehensive Systematic Review of Current Clinical Outcomes, Safety, and Arthroplasty Delay
Systematic Review with a reported sample of 5 on Knee Osteoarthritis, Osteoarthritis, Cartilage Damage, published in Cartilage (2026) — summary generated from the PubMed abstract.
- 2026
- n = 5
Cartilage - Level AMeta-analysisEurope PMC
Mesenchymal stem cell-derived extracellular vesicles for osteochondral defect regeneration: a systematic review and meta-analysis of preclinical studies
Meta-analysis on Cartilage Damage, published in J Transl Med (2026) — summary generated from the PubMed abstract.
- 2026
J Transl Med - Level ASystematic ReviewEurope PMC
The role of costal cartilage in musculoskeletal regeneration: A systematic review
Systematic Review on Cartilage Damage, published in J Exp Orthop (2026) — summary generated from the PubMed abstract.
- 2026
J Exp Orthop - Level ASystematic ReviewPubMed
A Comparison of the Properties of Mesenchymal Stem Cells Derived from Different Synovial Sources: A Systematic Review.
Systematic Review on Osteoarthritis, Cartilage Damage, published in Int J Mol Sci (2026) — summary generated from the PubMed abstract.
- 2026
Int J Mol Sci