Level B· Emerging Clinical Evidence
Efficacy and Safety of Cell-Assisted Lipotransfer: A Systematic Review and Meta-Analysis
Zhou Y., Wang J., Li H., Li Q.
Pooled 17 articles covering 387 cases to estimate fat survival rate along with complication and reoperation incidence.
- Study type
- Meta-analysis
- Journal
- Plastic and Reconstructive Surgery (2016)
- Country
- China
- Sample size
- 387
- Follow-up
- Varied across included studies
- PMID
- 26710060
- DOI
- 10.1097/PRS.0000000000001981
What was studied
Fat survival rate and safety of cell-assisted fat grafting.
Methods
- • Searched PubMed, Cochrane Library, EBSCO and EMBASE for studies published 2008–2014.
Key findings
- • Produced a pooled estimate of fat survival rate from available studies.
- • Reported complications were predominantly minor.
Limitations
- • Most included studies were not RCTs.
- • Data date back to 2008 when techniques differed from today.
What this study does not prove
- • This study does not prove SVF is an approved treatment or a replacement for standard care.
- • Limited follow-up cannot indicate long-term outcomes.
Clinical interpretation
An early but still frequently cited synthesis; read alongside more recent meta-analyses.
Evidence level: Emerging Clinical Evidence