Disc Degeneration

Disc degeneration attracts strong interest in regenerative medicine.

Studied for nucleus pulposus cell viability and matrix content.

Pilot studies mainly report short-term safety.

Reported adverse events are mostly local — swelling, pain, or bruising at the harvest and injection sites. Infection and cell-processing quality remain the key risks to monitor.

Existing studies are limited by sample size, methodology, and follow-up, and SVF preparation differs substantially between centres, making cross-study comparison difficult.