Level B· Emerging clinical evidence with positive signalsClinical TrialPubMed

Adipose tissue-derived stem cells: the friendly side of a classic cardiovascular foe.

Sanz-Ruiz R., Santos ME., Muñoa MD., Martín IL., Parma R., Fernández PL.

Clinical Trial on Cardiovascular Disease, published in J Cardiovasc Transl Res (2008) — summary generated from the PubMed abstract.

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Level B· Emerging clinical evidence with positive signalsEvidence level of this study

Several human studies show positive signals, while research methods and sample sizes continue to develop.

  • Level A · Stronger Clinical Evidence
  • Level B · Emerging clinical evidence with positive signals
  • Level C · Early human research exploring benefits
  • Level D · Scientific groundwork from lab and animal studies
  • Emerging · Emerging topic under active research
Read the A–D evidence level guide

This page is generated from the PubMed record. The Thai description is an automated summary of bibliographic fields and the abstract, not a full translation, and is not medical advice.

Study type
Clinical Trial
Journal
J Cardiovasc Transl Res (2008)
Country
United States
Reported sample size
—
Source database
PubMed
PMID
20559958
DOI
10.1007/s12265-007-9006-9
Citations
9

Abstract (original English)

Recently, the existence of a population of stem cells located in the adipose tissue has been observed. Adipose-derived stem cells are able to differentiate into multiple cell lineages including cardiac myocytes. Hence, adipose-derived cells are emerging as a new source of adult stem cells for cardiovascular repair. In this review, we discuss the basic principles of adipose-derived stem cells (types and characteristics, obtention processes, immunophenotypic characterization, and cell potency), the initial experimental studies, and the currently ongoing clinical trials.

What this study does not prove

  • • This study does not prove SVF is an approved treatment or a replacement for standard care.

Evidence level

Several human studies show positive signals, while research methods and sample sizes continue to develop.

How we grade evidence
Adipose TissueAdult Stem CellsAnimalsCell DifferentiationCell LineageCell ProliferationClinical Trials as TopicHeart DiseasesHumansMultipotent Stem Cells

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