Adoption of polyvinyl alcohol electrospinning materials for skin wound dressing

Evidence from laboratory and animal studies provides groundwork for understanding mechanisms and potential before human studies continue.

• Level A · Stronger Clinical Evidence
• Level B · Emerging clinical evidence with positive signals
• Level C · Early human research exploring benefits
• Level D · Scientific groundwork from lab and animal studies
• Emerging · Emerging topic under active research

Abstract (original English)

The effective treatment and repair of skin trauma has always been an important topic of medical research. As an advanced preparation method of nanofibers (NFs), electrospinning (ES) technology shows broad application prospects in the field of skin wound dressing. This review aims to systematically summarize and analyze the process and application research progress of PVA ES materials in skin wound dressing, and explore its mechanism and clinical application prospects in the process of wound healing. By consulting and analyzing the literature about PVA ES materials in recent years, the preparation process, structural properties, and application examples in skin wound dressing were focused on, and the latest experimental research and clinical data were combined to make a comprehensive review. The results suggested that PVA ES material had unique advantages in wound healing. NFs dressings with specific structure and properties can be prepared by adjusting ES parameters. PVA ES dressing not only has excellent physical barrier function, but also can regulate humidity, promote cell proliferation and angiogenesis, thus accelerating wound healing. In addition, the functionally modified PVA fiber dressing also suggested visible effects in antibacterial, anti-inflammatory, and other aspects. Visible progress has been made in the application of PVA ES materials in skin wound dressings. Ho

Evidence level

Evidence from laboratory and animal studies provides groundwork for understanding mechanisms and potential before human studies continue.

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