SVF
Level A· Stronger Clinical EvidenceSystematic Review

Adverse reactions associated with perioral rejuvenation using laser, fat and hyaluronic acid: systematic review.

Sayan A., Gonen ZB., Ilankovan V.

Systematic Review on Skin Aging, published in Br J Oral Maxillofac Surg (2021) — summary generated from the PubMed abstract.

This page is generated from the PubMed record. The Thai description is an automated summary of bibliographic fields and the abstract, not a full translation, and is not medical advice.

Study type
Systematic Review
Journal
Br J Oral Maxillofac Surg (2021)
Country
Scotland
Reported sample size
—
PMID
34284888
DOI
10.1016/j.bjoms.2021.02.027

Abstract (original English)

Perioral rejuvenation is carried out by surgical and non-surgical tools. The common procedures are laser resurfacing and volumanisation using alloplastic fillers or autogenous fat. Nonetheless, any such procedures are associated with complications. To evaluate a concise presentation of complications and safety associated with different perioral rejuvenation treatments including laser ablation, fat grafting and hyaluronic acid injections. A systematic literature review of all the relevant studies and case reports on complications and adverse reactions associated with laser ablation, administration of fillers and fat for the rejuvenation of perioral region. Twelve articles passed the inclusion criteria (as per PRISMA guidelines) and were scrupulously analysed. Four publications evaluated complications associated with laser resurfacing, five were related to filler augmentation and three were related to fat administration. The results concluded that all three aesthetic treatments are associated with mild to moderate complications. Severe complications are rare but can arise. Clinicians should be mindful of possible complications and able to recognise adverse events so that remedies could be executed with minimal delay. Training and supervision are essential components of ensuring provision of safe aesthetic treatment, and lack of regulation is a concern.

What this study does not prove

  • • This study does not prove SVF is an approved treatment or a replacement for standard care.

Evidence level

Relatively higher-quality human studies compared with other topics in this database, e.g. multiple RCTs or systematic reviews. This does not mean it is standard or approved care.

How we grade evidence
Cosmetic TechniquesEsthetics, DentalHumansHyaluronic AcidInjectionsLasersRejuvenationSkin Aging
Skin Aging
View on PubMedDOI

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