Level D· Scientific groundwork from lab and animal studiesNarrative ReviewPubMed

Autologous Fat Grafting of the Face in Men.

Nagappan L., Liao D., Bloom JD.

Narrative Review on Skin Aging, Facial Rejuvenation, published in Facial Plast Surg (2025) — summary generated from the PubMed abstract.

Open my reading list
Level D· Scientific groundwork from lab and animal studiesEvidence level of this study

Evidence from laboratory and animal studies provides groundwork for understanding mechanisms and potential before human studies continue.

  • Level A · Stronger Clinical Evidence
  • Level B · Emerging clinical evidence with positive signals
  • Level C · Early human research exploring benefits
  • Level D · Scientific groundwork from lab and animal studies
  • Emerging · Emerging topic under active research
Read the A–D evidence level guide

This page is generated from the PubMed record. The Thai description is an automated summary of bibliographic fields and the abstract, not a full translation, and is not medical advice.

Study type
Narrative Review
Journal
Facial Plast Surg (2025)
Country
United States
Reported sample size
—
Source database
PubMed
PMID
40972865
DOI
10.1055/a-2705-3478

Abstract (original English)

Men have distinct facial anatomy and facial patterns. Autologous fat grafting techniques can be tailored to maintain masculine features.Interest in male facial rejuvenation has grown in recent decades. Autologous fat grafting is favored for its natural, durable results and regenerative benefits.Men have angular facial structures with prominent brows, wider jaws, and thinner fat layers. Aging leads to forehead rhytids, midface hollowing, nasal lengthening, jawline blunting, and a more rectangular profile due to bone loss and skin laxity.Thorough preoperative evaluation and facial analysis are important for successful planning and outcomes.There are various commercially available tools for fat harvesting and processing. The Tulip cannula and PureGraft systems are described in this article. Microfat (1,000-1,500 microns) is preferred in facial grafting for its balance of volume restoration and low nodularity risk. The brow, infraorbital region, midface, jawline, and chin can be targeted to restore a youthful, masculine contour.Research on male-specific outcomes, including hormonal and weight effects on graft longevity and patient-reported outcomes, is limited and is an area ripe for future investigation.As interest in male aesthetics increases, tailoring facial rejuvenation techniques to their anatomy and aging is essential for successful outcomes.

What this study does not prove

  • • This study does not prove SVF is an approved treatment or a replacement for standard care.
  • • This is a narrative review: it collects no new patient data and does not systematically appraise evidence quality.

Evidence level

Evidence from laboratory and animal studies provides groundwork for understanding mechanisms and potential before human studies continue.

How we grade evidence
HumansMaleAdipose TissueFaceRejuvenationTransplantation, AutologousTissue and Organ HarvestingRhytidoplastyCannulaEsthetics

Browse all related research

Filter the research library by this study's title keywords, author, or publication year.

Related research