Autologous Fat Grafting of the Periorbital and Midface Areas.

Evidence from laboratory and animal studies provides groundwork for understanding mechanisms and potential before human studies continue.

• Level A · Stronger Clinical Evidence
• Level B · Emerging clinical evidence with positive signals
• Level C · Early human research exploring benefits
• Level D · Scientific groundwork from lab and animal studies
• Emerging · Emerging topic under active research

Abstract (original English)

Autologous fat grafting to the midface and periorbital regions offers a powerful solution for addressing age-related facial volume descent and depletion, contributing to a rejuvenated appearance. Herein, we explore the biological principles of fat grafting, the methodology for harvesting, processing, and injecting fat, and its application in facial aesthetics. We describe the role of different types of autologous fat in restoring volume and improving skin texture and quality. Finally, we discuss the evolving techniques aimed at enhancing graft retention and aesthetic outcomes with a focus on the midface and periorbital regions.

Evidence level

Evidence from laboratory and animal studies provides groundwork for understanding mechanisms and potential before human studies continue.

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