Bibliometric and visualized analysis of the therapeutic application of suprachoroidal space from 2000 to 2024

Several human studies show positive signals, while research methods and sample sizes continue to develop.

• Level A · Stronger Clinical Evidence
• Level B · Emerging clinical evidence with positive signals
• Level C · Early human research exploring benefits
• Level D · Scientific groundwork from lab and animal studies
• Emerging · Emerging topic under active research

Abstract (original English)

Objectives To provide a bibliometric overview of the global research on the therapeutic applications of the suprachoroidal space (SCS) from 2000 to 2024. Methods Publications were retrieved from the Web of Science Core Collection using a defined search strategy. A total of 776 articles were analyzed for trends in publication volume, countries, institutions, authorship, journals, citations, and keywords. An analysis of top 10% highly cited publications was also conducted. Co-authorship, co-occurrence, and citation burst analyses were conducted using VOSviewer, bibliometrix (R), and CiteSpace. Results Global publications on SCS therapy increased steadily, with a 575% growth. The United States led in output (n = 274, 35.3%) and international collaboration. Top institutions included the University of Melbourne, Bionics Institute, and Osaka University. Fujikado Takashi was the most prolific author (34 publications), while Prausnitz Mark R R had the highest citation impact (50 per article). Investigative Ophthalmology & Visual Science was the most active journal (n = 50; 2249 citations). Keyword analysis revealed three main clusters: (1) drug delivery, (2) glaucoma treatment, and (3) retinal prosthesis. Overlay map indicated that research foci have shift from implantation to injection, minimally invasive approach, and clinical trials. Burst keywords showed suprachoroidal drug deliver

Evidence level

Several human studies show positive signals, while research methods and sample sizes continue to develop.

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