Bioelectric Modulation as a Systems-Level Adjunct to Regenerative Therapies in Facial Plastic Surgery and Hair Restoration.
Leonhardt HJ., Keller GS., Pontius A.
Narrative Review on Chronic Wound, Skin Aging, Facial Rejuvenation, published in Facial Plast Surg Clin North Am (2026) — summary generated from the PubMed abstract.
This page is generated from the PubMed record. The Thai description is an automated summary of bibliographic fields and the abstract, not a full translation, and is not medical advice.
- Study type
- Narrative Review
- Journal
- Facial Plast Surg Clin North Am (2026)
- Country
- United States
- Reported sample size
- —
- PMID
- 42392657
- DOI
- 10.1016/j.fsc.2026.05.003
Abstract (original English)
Regenerative strategies in facial plastic surgery increasingly incorporate platelet-rich fibrin, platelet-rich plasma, fat grafting, and emerging biologic agents. Despite widespread adoption, outcomes remain variable, in part due to limited control of upstream processes such as perfusion, extracellular matrix remodeling, and stem cell niche stability. To review the mechanistic basis and emerging clinical evidence supporting bioelectric modulation as a systems-level regulator of regenerative pathways relevant to facial rejuvenation, wound healing, and hair restoration. Bioelectric modulation represents a plausible investigational adjunct to biologic therapies in facial plastic surgery. Further studies are required to define efficacy, optimize treatment parameters, and evaluate long-term safety.
What this study does not prove
- • This study does not prove SVF is an approved treatment or a replacement for standard care.
- • This is a narrative review: it collects no new patient data and does not systematically appraise evidence quality.
Evidence level
There is currently not enough data to draw conclusions about benefit or risk for this topic.
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