Level D· Scientific groundwork from lab and animal studiesNarrative ReviewEurope PMCOpen access

Bioprinting revolution: Innovative design of 3D bioactive scaffolds for living organs and transdermal tissues

Yücer S., Sarac B., Ciftci F.

Narrative Review on Chronic Wound, published in Bioeng Transl Med (2025) — summary generated from the PubMed abstract.

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Level D· Scientific groundwork from lab and animal studiesEvidence level of this study

Evidence from laboratory and animal studies provides groundwork for understanding mechanisms and potential before human studies continue.

  • Level A · Stronger Clinical Evidence
  • Level B · Emerging clinical evidence with positive signals
  • Level C · Early human research exploring benefits
  • Level D · Scientific groundwork from lab and animal studies
  • Emerging · Emerging topic under active research
Read the A–D evidence level guide

This page is generated from the PubMed record. The Thai description is an automated summary of bibliographic fields and the abstract, not a full translation, and is not medical advice.

Study type
Narrative Review
Journal
Bioeng Transl Med (2025)
Reported sample size
—
Source database
Europe PMC
PMID
41244329
PMCID
PMC12617564
DOI
10.1002/btm2.70080
Citations
1

Abstract (original English)

The bioprinting revolution has opened new frontiers in the design and fabrication of three-dimensional bioactive scaffolds for living organs and transdermal tissues. This transformative technology enables the precise assembly of biomaterials and living cells, creating structures that mimic the complexity of natural tissues. Advances in bioprinting have facilitated the development of personalized scaffolds for tissue regeneration, wound healing, and transdermal drug delivery systems. This abstract explores cutting-edge innovations in bioactive scaffold design, highlighting their potential to replicate functional organ structures and support transdermal therapeutic applications. Current challenges, such as achieving vascularization and mechanical integrity, are discussed alongside emerging solutions and future directions for clinical translation. Bioprinting stands poised to redefine the landscape of regenerative medicine and transdermal therapeutics.

What this study does not prove

  • • This study does not prove SVF is an approved treatment or a replacement for standard care.
  • • This is a narrative review: it collects no new patient data and does not systematically appraise evidence quality.

Evidence level

Evidence from laboratory and animal studies provides groundwork for understanding mechanisms and potential before human studies continue.

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