Level D· Scientific groundwork from lab and animal studiesNarrative ReviewEurope PMC

Cardiac stem cell biology: glimpse of the past, present, and future

Matsa E., Sallam K., Wu JC.

Narrative Review on Cardiovascular Disease, published in Circ Res (2014) — summary generated from the PubMed abstract.

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Level D· Scientific groundwork from lab and animal studiesEvidence level of this study

Evidence from laboratory and animal studies provides groundwork for understanding mechanisms and potential before human studies continue.

  • Level A · Stronger Clinical Evidence
  • Level B · Emerging clinical evidence with positive signals
  • Level C · Early human research exploring benefits
  • Level D · Scientific groundwork from lab and animal studies
  • Emerging · Emerging topic under active research
Read the A–D evidence level guide

This page is generated from the PubMed record. The Thai description is an automated summary of bibliographic fields and the abstract, not a full translation, and is not medical advice.

Study type
Narrative Review
Journal
Circ Res (2014)
Reported sample size
—
Source database
Europe PMC
PMID
24385505
PMCID
PMC6430634
DOI
10.1161/circresaha.113.302895
Citations
40

Abstract (original English)

Cardiac regeneration strategies and de novo generation of cardiomyocytes have long been significant areas of research interest in cardiovascular medicine. In this review, we outline a variety of common cell sources and methods used to regenerate cardiomyocytes and highlight the important role that key Circulation Research articles have played in this flourishing field.

What this study does not prove

  • • This study does not prove SVF is an approved treatment or a replacement for standard care.
  • • This is a narrative review: it collects no new patient data and does not systematically appraise evidence quality.

Evidence level

Evidence from laboratory and animal studies provides groundwork for understanding mechanisms and potential before human studies continue.

How we grade evidence
HeartMyocytes, CardiacStem CellsAnimalsHumansHeart DiseasesStem Cell TransplantationRegenerationCell DifferentiationHistory, 20th Century

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