Cell-engineered technologies for wound healing and tissue regeneration

Evidence from laboratory and animal studies provides groundwork for understanding mechanisms and potential before human studies continue.

• Level A · Stronger Clinical Evidence
• Level B · Emerging clinical evidence with positive signals
• Level C · Early human research exploring benefits
• Level D · Scientific groundwork from lab and animal studies
• Emerging · Emerging topic under active research

Abstract (original English)

This review provides a comprehensive analysis of diverse cell-engineered technologies for wound healing and tissue regeneration, highlighting various engineered techniques in a single article. It discusses different types of genetic modifications in various cell types to enhance cellular therapeutic properties. It also explores innovative cell delivery systems, including hydrogels and 3D bioprinting. Additionally, we evaluate the clinical applicability of these technologies and highlight key challenges, providing a future research direction.

Evidence level

Evidence from laboratory and animal studies provides groundwork for understanding mechanisms and potential before human studies continue.

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