Level C· Early human research exploring benefitsRetrospective StudyEurope PMCOpen access

Clinical evaluation of day surgery for anal fistula excision with MRI-assisted diagnosis: a retrospective analysis of 121 cases

Zhang S., Chen F., Wei Y., Ma X., Lu H., Luo Y.

Retrospective Study with a reported sample of 121 on Chronic Wound, Autoimmune Research, published in Front Med (Lausanne) (2025) — summary generated from the PubMed abstract.

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Level C· Early human research exploring benefitsEvidence level of this study

Early human evidence such as case series or small samples is exploring possible benefits.

  • Level A · Stronger Clinical Evidence
  • Level B · Emerging clinical evidence with positive signals
  • Level C · Early human research exploring benefits
  • Level D · Scientific groundwork from lab and animal studies
  • Emerging · Emerging topic under active research
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This page is generated from the PubMed record. The Thai description is an automated summary of bibliographic fields and the abstract, not a full translation, and is not medical advice.

Study type
Retrospective Study
Journal
Front Med (Lausanne) (2025)
Reported sample size
121
Source database
Europe PMC
PMID
40495958
PMCID
PMC12149161
DOI
10.3389/fmed.2025.1579652

Abstract (original English)

Objective The clinical practice of anal fistula excision surgeries conducted in the day surgery unit was analyzed, and the efficacy and safety of this surgery were evaluated. Methods The clinical data of 121 patients with anal fistulas who underwent excision surgery at Changhai Hospital from October 2021 to April 2024 was retrospectively analyzed, including age, gender, body mass index (BMI), diagnosis, fistula characteristics (number and locations of internal and external openings), preoperative magnetic resonance imaging (MRI) of fistulas, surgical and anesthetic methods, length of hospital stay, verbal rating scale (VRS), outpatient follow-up frequency, wound healing status, rehabilitation time, postoperative complications, and patient satisfaction. Kappa statistics were employed to evaluate the value of MRI in assessing the Parks classification and the number of fistulas compared with that of intraoperative findings. Results All 121 patients successfully underwent anal fistula excision or excision combined with seton placement, with no patients lost to follow-up. All patients fully recovered, achieving a cure rate of 100%. Postoperative complications were rare, with only one patient (0.3%) experiencing pruritus and no recurrence. The rate of patient satisfaction reached 96.7%. The accuracies of the Park classification and number of fistulas assessed by MRI were 95.9 and 94.

What this study does not prove

  • • This study does not prove SVF is an approved treatment or a replacement for standard care.
  • • Without an adequate control group, treatment effects cannot be separated from other factors.

Evidence level

Early human evidence such as case series or small samples is exploring possible benefits.

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