Level C· Early human research exploring benefitsCase Report / SeriesPubMed

Combined Non-Ablative Laser and Microfat Grafting for Burn Scar Treatment.

Onur Erol O., Agaoglu G., Jawad MA.

Case Report / Series with a reported sample of 288 on Burns, Scar, published in Aesthet Surg J (2019) — summary generated from the PubMed abstract.

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Level C· Early human research exploring benefitsEvidence level of this study

Early human evidence such as case series or small samples is exploring possible benefits.

  • Level A · Stronger Clinical Evidence
  • Level B · Emerging clinical evidence with positive signals
  • Level C · Early human research exploring benefits
  • Level D · Scientific groundwork from lab and animal studies
  • Emerging · Emerging topic under active research
Read the A–D evidence level guide

This page is generated from the PubMed record. The Thai description is an automated summary of bibliographic fields and the abstract, not a full translation, and is not medical advice.

Study type
Case Report / Series
Journal
Aesthet Surg J (2019)
Country
England
Reported sample size
288
Source database
PubMed
PMID
30403775
DOI
10.1093/asj/sjy291
Citations
17

Abstract (original English)

Background Burn scar treatment persists as an unsolved problem, involving thousands of affected patients disfigured for life. Objectives We sought to present our experience with the use of combined treatments for patients with burn scars. Methods This was a case series report of the senior author's experience during 8 years utilizing the combined treatments of Fraxel Restore (fractional laser) and microfat graft injection for 288 patients with burn scars. Results Laser treatment reduced scar intensity and attenuated skin irregularities and hyperpigmentation. All patients demonstrated marked improvement of skin texture and an increase in scar softness after 3 sessions of microfat grafting. However, the degree of improvement varied between patients and was related to the severity of the scar and the type of tissue. Overall, a 40% to 80% improvement was noted in our patients. All patients and their families expressed satisfaction with the results. Conclusions The combined treatment of Fraxel and microfat grafting is an effective technique for improving the appearance of a hypertrophic scar or keloid on burn patients. Fat tissue stem cells may have helped to repair the damaged skin. Level of evidence: 4

What this study does not prove

  • • This study does not prove SVF is an approved treatment or a replacement for standard care.
  • • Without an adequate control group, treatment effects cannot be separated from other factors.

Evidence level

Early human evidence such as case series or small samples is exploring possible benefits.

How we grade evidence
Adipose TissueAdolescentAdultBurnsChildChild, PreschoolCicatrixCicatrix, HypertrophicCombined Modality TherapyFemale

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