Level D· Scientific groundwork from lab and animal studiesAnimal StudyEurope PMCOpen access

Fluorescent Light Energy in Feline Surgical and Traumatic Wounds: A Prospective Single-Arm Pilot Study of Healing Progression and Bacterial Findings

Nocera FP., Fantini O., Abate G., Sangiuliano C., Piantedosi D., Marchitelli M.

Animal Study on Chronic Wound, published in Vet Med Sci (2026) — summary generated from the PubMed abstract.

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Level D· Scientific groundwork from lab and animal studiesEvidence level of this study

Evidence from laboratory and animal studies provides groundwork for understanding mechanisms and potential before human studies continue.

  • Level A · Stronger Clinical Evidence
  • Level B · Emerging clinical evidence with positive signals
  • Level C · Early human research exploring benefits
  • Level D · Scientific groundwork from lab and animal studies
  • Emerging · Emerging topic under active research
Read the A–D evidence level guide

This page is generated from the PubMed record. The Thai description is an automated summary of bibliographic fields and the abstract, not a full translation, and is not medical advice.

Study type
Animal Study
Journal
Vet Med Sci (2026)
Reported sample size
—
Source database
Europe PMC
PMID
41965937
PMCID
PMC13070025
DOI
10.1002/vms3.70929

Abstract (original English)

Background Traumatic and surgical wounds are common in cats, but their management is often challenging due to anatomical factors, delayed presentation, behavioural issues and frequent bacterial colonization. Objectives This prospective, single-arm study aimed to evaluate feasibility and tolerance, and to describe changes in TIME wound scores and bacterial findings during a standardized FLE protocol in cats with surgical or traumatic skin lesions. FLE's potential had been shown in dogs but was previously unexplored in feline wound care. Methods A total of 17 cats with various skin lesions were included in the trial. Each cat received three weekly FLE sessions. Before each session (T0, T1 and T2), skin swabs were collected for microbiological analysis. No systemic or topical antibiotics were administered. Wound healing was assessed using the TIME (tissue, inflammation, moisture and epithelialization) scoring system at baseline (T0), Day 7 (T1) and Day 14 (T2). Results and conclusions Significant improvements in all TIME parameters (p < 0.01) were observed. The composite wound score decreased by 73% from baseline. At T2, 82% of cats had no necrotic tissue, 65% showed complete inflammation resolution, and epithelialization had improved in 41% of cases. While multidrug-resistant bacteria were found in 41% of cases, their presence did not prevent healing, and five cats achieved negat

What this study does not prove

  • • This study does not prove SVF is an approved treatment or a replacement for standard care.
  • • This is preclinical work; animal or laboratory results cannot be applied to humans.

Evidence level

Evidence from laboratory and animal studies provides groundwork for understanding mechanisms and potential before human studies continue.

How we grade evidence
AnimalsCatsWounds and InjuriesCat DiseasesProspective StudiesPilot ProjectsWound HealingFluorescenceFemaleMale

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