Level D· Scientific groundwork from lab and animal studiesNarrative ReviewPubMed

New Progress of Adipose-derived Stem Cells in the Therapy of Hypertrophic Scars.

He X., Zhang J., Luo L., Shi J., Hu D.

Narrative Review on Chronic Wound, Burns, Scar, published in Curr Stem Cell Res Ther (2020) — summary generated from the PubMed abstract.

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Level D· Scientific groundwork from lab and animal studiesEvidence level of this study

Evidence from laboratory and animal studies provides groundwork for understanding mechanisms and potential before human studies continue.

  • Level A · Stronger Clinical Evidence
  • Level B · Emerging clinical evidence with positive signals
  • Level C · Early human research exploring benefits
  • Level D · Scientific groundwork from lab and animal studies
  • Emerging · Emerging topic under active research
Read the A–D evidence level guide

This page is generated from the PubMed record. The Thai description is an automated summary of bibliographic fields and the abstract, not a full translation, and is not medical advice.

Study type
Narrative Review
Journal
Curr Stem Cell Res Ther (2020)
Country
United Arab Emirates
Reported sample size
—
Source database
PubMed
PMID
31483236
DOI
10.2174/1574888X14666190904125800
Citations
4

Abstract (original English)

Burns are a global public health issue of great concern. The formation of scars after burns and physical dysfunction of patients remain major challenges in the treatment of scars. Regenerative medicine based on cell therapy has become a hot topic in this century. Adipose-derived stem cells (ADSCs) play an important role in cellular therapy and have become a promising source of regenerative medicine and wound repair transplantation. However, the anti-scarring mechanism of ADSCs is still unclear yet. With the widespread application of ADSCs in medical, we firmly believe that it will bring great benefits to patients with hypertrophic scars.

What this study does not prove

  • • This study does not prove SVF is an approved treatment or a replacement for standard care.
  • • This is a narrative review: it collects no new patient data and does not systematically appraise evidence quality.

Evidence level

Evidence from laboratory and animal studies provides groundwork for understanding mechanisms and potential before human studies continue.

How we grade evidence
AdipocytesAnimalsCell DifferentiationCicatrix, HypertrophicGuided Tissue RegenerationHumansMesenchymal Stem Cell TransplantationMesenchymal Stem CellsTissue ScaffoldsWound Healing

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