Nipple Preservation through Partial Nipple Incision and Partial Areola Resection for a Breast Cancer Adjacent to the Nipple-Areolar Complex

Early human evidence such as case series or small samples is exploring possible benefits.

• Level A · Stronger Clinical Evidence
• Level B · Emerging clinical evidence with positive signals
• Level C · Early human research exploring benefits
• Level D · Scientific groundwork from lab and animal studies
• Emerging · Emerging topic under active research

Abstract (original English)

A 45-year-old woman with a tumor just beneath the left areola was referred to our hospital. Magnetic resonance imaging (MRI) findings made us perform a core needle biopsy of the tumor, leading to the diagnosis of invasive lobular carcinoma (cT1N0M0). MRI also depicted three daughter nodules located medially to the main tumor in a linear fashion. Patient's strong request for nipple preservation made us try to resect the breast cancer in a manner to possibly preserve the nipple-areolar complex. First, to resect the target four tumors, medial horizontal skin incision at the nipple level and subsequent lower semicircular peri-areolar incision were done to the left breast. Second, small skin resection in a triangle shape and a radial fashion from the nipple bottom, i.e., orthogonal skin resection to the peri-areolar incision, was done to the areola just above the main tumor. Third, the triangle resection line was extended to the center of the parietal part of the nipple via a longitudinal skin incision on the lateral side of the nipple. Intra-nipple tissue adjacent to the sub-areolar tumor was resected as much as possible. Partially resected areola and partially incised nipple were sutured into the original shape. Pathological study showed invasive lobular carcinoma with lymphovascular invasion and widespread, i.e., total size of 60 mm, noninvasive lobular carcinoma and negative sur

Evidence level

Early human evidence such as case series or small samples is exploring possible benefits.

Browse all related research

Filter the research library by this study's title keywords, author, or publication year.