An overview on electrospinning and its advancement toward hard and soft tissue engineering applications

Evidence from laboratory and animal studies provides groundwork for understanding mechanisms and potential before human studies continue.

• Level A · Stronger Clinical Evidence
• Level B · Emerging clinical evidence with positive signals
• Level C · Early human research exploring benefits
• Level D · Scientific groundwork from lab and animal studies
• Emerging · Emerging topic under active research

Abstract (original English)

One of the emerging technologies of the recent times harboring nanotechnology to fabricate nanofibers for various biomedical and environmental applications are electrospinning (nanofiber technology). Their relative ease in use, simplicity, functionality and diversity has surpassed the pitfalls encountered with the conventional method of generating fibers. This review aims to provide an overview of electrospinning, principle, methods, feed materials, and applications toward tissue engineering. To begin with, evolution of electrospinning and its typical apparatus have been briefed. Simultaneously, discussion on the production of nanofibers with diversified feed materials such as polymers, small molecules, colloids, and nanoparticles and its transformation into a powerful technology has been dealt with. Further, highlights on the application of nanofibers in tissue engineering and the commercialized products developed using nanofiber technology have been summed up. With this rapidly emerging technology, there would be a great demand pertaining to scalability and environmental challenge toward tissue engineering applications.

Evidence level

Evidence from laboratory and animal studies provides groundwork for understanding mechanisms and potential before human studies continue.

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