Level C· Early human research exploring benefitsCase Report / SeriesPubMedOpen access

Platelet-rich Plasma Injection and Lipofilling-assisted Hair Transplantation on Residual Scalp Alopecia Post Aplasia Cutis Congenita Verticis (ACCV).

Montonati E., Codolini L., Montonati C., Tarsitano MG., Carbonaro R., Sanese G.

Case Report / Series on Hair Loss, published in Int J Trichology (2025) — summary generated from the PubMed abstract.

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Level C· Early human research exploring benefitsEvidence level of this study

Early human evidence such as case series or small samples is exploring possible benefits.

  • Level A · Stronger Clinical Evidence
  • Level B · Emerging clinical evidence with positive signals
  • Level C · Early human research exploring benefits
  • Level D · Scientific groundwork from lab and animal studies
  • Emerging · Emerging topic under active research
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This page is generated from the PubMed record. The Thai description is an automated summary of bibliographic fields and the abstract, not a full translation, and is not medical advice.

Study type
Case Report / Series
Journal
Int J Trichology (2025)
Country
India
Reported sample size
—
Source database
PubMed
PMID
41306833
PMCID
PMC12646517
DOI
10.4103/ijt.ijt_125_23

Abstract (original English)

Aplasia cutis congenita (ACC) is a rare congenital disorder characterized by the absence at birth, of skin, dermal appendages, and, in some cases, subcutaneous tissues. The scalp is the most commonly affected area. Usually, particularly after conservative or minimally invasive management at birth, it results in an area of alopecia. We describe a case of post-ACC alopecia of the scalp treated with follicular unit transplantation, combined with platelet-rich plasma and fat grafting. In our patient, this combined therapeutic strategy induced radical modifications of hair follicles, skin quality, and also sensitivity of the affected area.

What this study does not prove

  • • This study does not prove SVF is an approved treatment or a replacement for standard care.
  • • Without an adequate control group, treatment effects cannot be separated from other factors.

Evidence level

Early human evidence such as case series or small samples is exploring possible benefits.

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