Level C· Early human research exploring benefitsProspective StudyEurope PMCOpen access

Prevention of Pressure Sore Recurrence with Fat Graft: Outcome Analysis with Recurrence, Thickness, and Scar-A Pilot Study

Troup O., Blažková B., Troupová M., Skalický A., Třešková I.

Prospective Study on Chronic Wound, Scar, published in Arch Plast Surg (2026) — summary generated from the PubMed abstract.

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Level C· Early human research exploring benefitsEvidence level of this study

Early human evidence such as case series or small samples is exploring possible benefits.

  • Level A · Stronger Clinical Evidence
  • Level B · Emerging clinical evidence with positive signals
  • Level C · Early human research exploring benefits
  • Level D · Scientific groundwork from lab and animal studies
  • Emerging · Emerging topic under active research
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This page is generated from the PubMed record. The Thai description is an automated summary of bibliographic fields and the abstract, not a full translation, and is not medical advice.

Study type
Prospective Study
Journal
Arch Plast Surg (2026)
Reported sample size
—
Source database
Europe PMC
PMID
41625399
PMCID
PMC12858314
DOI
10.1055/a-2702-1486

Abstract (original English)

Background Pressure ulcers are a common and debilitating complication in patients with spinal cord injuries (SCIs), often requiring reconstructive surgery. However, scarred areas remain vulnerable to recurrence. This study evaluates lipografting as a secondary prevention strategy to enhance soft tissue padding over bony prominences and reduce ulcer recurrence. Additionally, it investigates whether fat resorption rates are higher in compromised tissue. Methods Five wheelchair-bound male patients with SCIs who had previously undergone reconstructive surgery for ischial pressure sores were included. Lipografting was performed, and soft tissue thickness was measured using ultrasonography preoperatively, immediately postoperatively, and at 3 and 12 months. Scar pliability, patient satisfaction, and fat resorption rates in the compromised area were also assessed. Results Significant soft tissue augmentation was observed immediately postoperatively, with an average retention rate of 60.7% at 1 year. Scar pliability improved in all patients, and no new pressure ulcers developed during the follow-up period. Patients reported high satisfaction, with one noting increased tolerance for prolonged sitting. Conclusion Lipografting appears to be a promising, minimally invasive approach for secondary prevention of pressure ulcer recurrence in SCI patients. While these findings are encouraging,

What this study does not prove

  • • This study does not prove SVF is an approved treatment or a replacement for standard care.

Evidence level

Early human evidence such as case series or small samples is exploring possible benefits.

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