Recent advances in the development of hydrogel dressings for the treatment of pressure ulcers/injuries

Evidence from laboratory and animal studies provides groundwork for understanding mechanisms and potential before human studies continue.

• Level A · Stronger Clinical Evidence
• Level B · Emerging clinical evidence with positive signals
• Level C · Early human research exploring benefits
• Level D · Scientific groundwork from lab and animal studies
• Emerging · Emerging topic under active research

Abstract (original English)

Pressure ulcers, also known as pressure injuries, are common conditions that result from chronic bedrest. These ulcers significantly affect quality of life and substantially burden individuals and society with health costs. The prevention and treatment of pressure ulcers is a primary concern for health care professionals. Dressings play a crucial role in the treatment of pressure ulcers. Hydrogels are innovative safe materials that show great promise for clinical applications. Recent research has demonstrated the potential of hydrogel dressings to promote the healing of pressure ulcers and chronic wounds. This review aims to summarize the mechanisms and effects of hydrogel dressings and to discuss considerations for their use in patients with pressure injuries under different circumstances. Hydrogel dressings, especially loaded with unique cargo, may represent promising new options for the treatment of pressure ulcers. However, additional clinical studies are urgently needed to validate the efficacy and accessibility of hydrogels in clinical practice.

Evidence level

Evidence from laboratory and animal studies provides groundwork for understanding mechanisms and potential before human studies continue.

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