Level C· Early human research exploring benefitsProspective StudyPubMed

Resolution of refractory chronic autoimmune thrombocytopenic purpura following mesenchymal stem cell transplantation: a case report.

Fang B., Song YP., Li N., Li J., Han Q., Zhao RC.

Prospective Study on Autoimmune Research, published in Transplant Proc (2009) — summary generated from the PubMed abstract.

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Level C· Early human research exploring benefitsEvidence level of this study

Early human evidence such as case series or small samples is exploring possible benefits.

  • Level A · Stronger Clinical Evidence
  • Level B · Emerging clinical evidence with positive signals
  • Level C · Early human research exploring benefits
  • Level D · Scientific groundwork from lab and animal studies
  • Emerging · Emerging topic under active research
Read the A–D evidence level guide

This page is generated from the PubMed record. The Thai description is an automated summary of bibliographic fields and the abstract, not a full translation, and is not medical advice.

Study type
Prospective Study
Journal
Transplant Proc (2009)
Country
United States
Reported sample size
—
Source database
PubMed
PMID
19545737
DOI
10.1016/j.transproceed.2008.12.031

Abstract (original English)

Herein we have reported the case of a man with chronic autoimmune thrombocytopenia (AITP) refractory to conventional therapy who underwent T-cell-depleted autologous peripheral blood stem cell (PBSC) transplantation. A complete, steroid-independent, platelet remission was obtained, but unfortunately he subsequently relapsed after 3 months. Finally, we administered human adipose tissue-derived mesenchymal stem cells (AMSC) with resolution to the AITP.

What this study does not prove

  • • This study does not prove SVF is an approved treatment or a replacement for standard care.

Evidence level

Early human evidence such as case series or small samples is exploring possible benefits.

How we grade evidence
Granulocyte Colony-Stimulating FactorHematopoiesisHematopoietic Stem Cell MobilizationHumansInfusions, IntravenousLeukocyte CountMaleMesenchymal Stem Cell TransplantationNeutrophilsPlatelet Count

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