Level D· Scientific groundwork from lab and animal studiesNarrative ReviewEurope PMCOpen access

Short histological kaleidoscope - recent findings in histology. Part V. About tendons, ligaments, and cartilages

Jianu EM., Mihu CM., Sufleţel RT., Crivii CB., Constantin AM., Mocan LP.

Narrative Review on Meniscus Injury, Tendon Injury, Ligament Injury, published in Rom J Morphol Embryol (2025) — summary generated from the PubMed abstract.

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Level D· Scientific groundwork from lab and animal studiesEvidence level of this study

Evidence from laboratory and animal studies provides groundwork for understanding mechanisms and potential before human studies continue.

  • Level A · Stronger Clinical Evidence
  • Level B · Emerging clinical evidence with positive signals
  • Level C · Early human research exploring benefits
  • Level D · Scientific groundwork from lab and animal studies
  • Emerging · Emerging topic under active research
Read the A–D evidence level guide

This page is generated from the PubMed record. The Thai description is an automated summary of bibliographic fields and the abstract, not a full translation, and is not medical advice.

Study type
Narrative Review
Journal
Rom J Morphol Embryol (2025)
Reported sample size
—
Source database
Europe PMC
PMID
40851240
PMCID
PMC12509514
DOI
10.47162/rjme.66.2.03

Abstract (original English)

Tendons, ligaments, and various types of cartilage, including elastic, hyaline, growth, articular, and meniscal cartilage, share important structural and functional properties. As connective tissues, they are characterized by a dense extracellular matrix composed of collagen fibers and proteoglycans, which provide mechanical strength and flexibility. Their limited vascularity affects healing potential and metabolic activity. These tissues are crucial for maintaining joint integrity, distributing mechanical loads, and supporting skeletal development. This overview highlights the common features that define these connective tissues, providing a foundation for further understanding of their roles in musculoskeletal physiology and pathology, their capacity for regeneration, and possible treatment options.

What this study does not prove

  • • This study does not prove SVF is an approved treatment or a replacement for standard care.
  • • This is a narrative review: it collects no new patient data and does not systematically appraise evidence quality.

Evidence level

Evidence from laboratory and animal studies provides groundwork for understanding mechanisms and potential before human studies continue.

How we grade evidence
CartilageLigamentsTendonsAnimalsHumans

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