Level D· Scientific groundwork from lab and animal studiesLaboratory StudyPubMedOpen access

Successful Treatment of Vulvar Lichen Sclerosus Using Microfiltered and Preconditioned Suspension of Autologous Adipose-Derived Stem Cells With Photothermal Biomodulation: A Case Report.

Mezzana P., Pinto H.

Laboratory Study on Autoimmune Research, published in Clin Case Rep (2025) — summary generated from the PubMed abstract.

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Level D· Scientific groundwork from lab and animal studiesEvidence level of this study

Evidence from laboratory and animal studies provides groundwork for understanding mechanisms and potential before human studies continue.

  • Level A · Stronger Clinical Evidence
  • Level B · Emerging clinical evidence with positive signals
  • Level C · Early human research exploring benefits
  • Level D · Scientific groundwork from lab and animal studies
  • Emerging · Emerging topic under active research
Read the A–D evidence level guide

This page is generated from the PubMed record. The Thai description is an automated summary of bibliographic fields and the abstract, not a full translation, and is not medical advice.

Study type
Laboratory Study
Journal
Clin Case Rep (2025)
Country
England
Reported sample size
—
Source database
PubMed
PMID
41113289
PMCID
PMC12527820
DOI
10.1002/ccr3.71261

Abstract (original English)

Vulvar lichen sclerosus is a chronic, inflammatory, autoimmune mucocutaneous disease characterized by hypopigmentation, skin sclerosis, and atrophy. Injections with microfiltered and preconditioned suspension of autologous adipose-derived stem cells are well tolerated and reduce symptoms and skin sclerosis without side effects or technical complications. Results are valid for 5 months after treatment (follow-up period).

What this study does not prove

  • • This study does not prove SVF is an approved treatment or a replacement for standard care.
  • • This is preclinical work; animal or laboratory results cannot be applied to humans.

Evidence level

Evidence from laboratory and animal studies provides groundwork for understanding mechanisms and potential before human studies continue.

How we grade evidence

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