Level A· Stronger Clinical EvidenceSystematic ReviewPubMedOpen access

Systematic Review: Periareolar Mastopexy with Breast Implants and Fat Grafting.

Gentile P., De Angelis B.

Systematic Review with a reported sample of 1165 on Chronic Wound, published in Aesthetic Plast Surg (2025) — summary generated from the PubMed abstract.

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Level A· Stronger Clinical EvidenceEvidence level of this study

Relatively higher-quality human studies compared with other topics in this database, e.g. multiple RCTs or systematic reviews. This does not mean it is standard or approved care.

  • Level A · Stronger Clinical Evidence
  • Level B · Emerging clinical evidence with positive signals
  • Level C · Early human research exploring benefits
  • Level D · Scientific groundwork from lab and animal studies
  • Emerging · Emerging topic under active research
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This page is generated from the PubMed record. The Thai description is an automated summary of bibliographic fields and the abstract, not a full translation, and is not medical advice.

Study type
Systematic Review
Journal
Aesthetic Plast Surg (2025)
Country
United States
Reported sample size
1165
Source database
PubMed
PMID
40764885
PMCID
PMC12738600
DOI
10.1007/s00266-025-05116-z

Abstract (original English)

Background Periareolar mastopexy (PM) is a widely used technique for breast lift surgery, often combined with implants to improve breast volume. In recent years, autologous fat grafting (FG) has emerged as an adjunct to PM, enhancing contour and soft tissue volume. Objectives This article aimed to assess the complication rate, patient satisfaction, aesthetic outcomes, and long-term PM results combined with breast implants (BI) and FG. Methods A systematic review was performed using PubMed, MEDLINE, Web of Science, Embase, PreMEDLINE, EBase, CINAHL, Clinicaltrials.gov, Scopus, and Cochrane databases. The protocol was developed following the Preferred Reporting for Items for Systematic Reviews-Protocols (PRISMA-P) guidelines. The included studies had to match predetermined criteria according to the PICOS approach. Results A total of 13 studies with 1165 patients were included. The results showed a significant improvement in patient satisfaction, with 85% of patients reporting high satisfaction levels. The complication rate was relatively low, with capsular contracture (7.3%), fat absorption (9.7%), and wound healing issues (4.9%) being the most common. Aesthetic outcomes, measured by breast symmetry and shape, showed favorable results in 78.2% of patients. The combination of PM with BI and FG improved the breast's volume and contour, providing a more natural outcome than BI alone

What this study does not prove

  • • This study does not prove SVF is an approved treatment or a replacement for standard care.

Evidence level

Relatively higher-quality human studies compared with other topics in this database, e.g. multiple RCTs or systematic reviews. This does not mean it is standard or approved care.

How we grade evidence
AdultFemaleHumansMiddle AgedAdipose TissueBreast ImplantationBreast ImplantsEstheticsMammaplastyNipples

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