Level C· Early human research exploring benefitsProspective StudyPubMed

[Treatment of perianal fistulas with mesenchymal stem cells].

Dalby HR., Perregaard H., Dige A., Hagen KB., Nordholm-Carstensen A., Lundby L.

Prospective Study on Autoimmune Research, published in Ugeskr Laeger (2022) — summary generated from the PubMed abstract.

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Level C· Early human research exploring benefitsEvidence level of this study

Early human evidence such as case series or small samples is exploring possible benefits.

  • Level A · Stronger Clinical Evidence
  • Level B · Emerging clinical evidence with positive signals
  • Level C · Early human research exploring benefits
  • Level D · Scientific groundwork from lab and animal studies
  • Emerging · Emerging topic under active research
Read the A–D evidence level guide

This page is generated from the PubMed record. The Thai description is an automated summary of bibliographic fields and the abstract, not a full translation, and is not medical advice.

Study type
Prospective Study
Journal
Ugeskr Laeger (2022)
Country
Denmark
Reported sample size
—
Source database
PubMed
PMID
35410650

Abstract (original English)

Treatment of perianal fistulas are challenged by insufficient healing and a high rate of relapse. Existing sphincter-sparing procedures have healing rates of around 50%. Treatment with mesenchymal stem cells of both autologous and allogenic origin and freshly collected autologous adipose tissue show both promising healing rates and few complications and may be offered to patients with complicated fistulas not suited for other treatment modalities.

What this study does not prove

  • • This study does not prove SVF is an approved treatment or a replacement for standard care.

Evidence level

Early human evidence such as case series or small samples is exploring possible benefits.

How we grade evidence
Anal CanalCutaneous FistulaHumansMesenchymal Stem Cell TransplantationMesenchymal Stem CellsOrgan Sparing TreatmentsRectal FistulaTreatment Outcome

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