Condition
Diabetic Foot
Chronic-wound research in diabetes reports wound-closure rates.
Quick summary
- • Primary outcome is wound closure rate
Overview
Diabetic foot ulcers heal slowly and carry amputation risk, prompting varied research.
Mechanisms studied
Studied for angiogenesis and wound healing.
Human research
Small-to-medium clinical trials report some positive findings.
Safety
Reported adverse events are mostly local — swelling, pain, or bruising at the harvest and injection sites. Infection and cell-processing quality remain the key risks to monitor.
Evidence limitations
Existing studies are limited by sample size, methodology, and follow-up, and SVF preparation differs substantially between centres, making cross-study comparison difficult.
Related research
- Level BMeta-analysis
The efficiency of human fat products in wound healing: A systematic review and meta-analysis
Pooled 21 RCTs of autologous fat, SVF or ADSCs, finding faster healing rate, shorter healing time and more complete healing versus conventional treatment.
- 2024
- China
- InsufficientLaboratory Study
Therapeutic application of adipose-derived stromal vascular fraction in diabetic foot
Review describing diabetic foot pathogenesis, current treatments, and vascular remodelling as the proposed mechanism behind SVF effects.
- 2020
- China
Last updated: 2026-06-18 · arisa-w