MICRO-FRAGMENTED ADIPOSE TISSUE IN THE KNEE OSTEOARTHRITIS UNDER LOCAL ANESTHESIA

Evidence from laboratory and animal studies provides groundwork for understanding mechanisms and potential before human studies continue.

• Level A · Stronger Clinical Evidence
• Level B · Emerging clinical evidence with positive signals
• Level C · Early human research exploring benefits
• Level D · Scientific groundwork from lab and animal studies
• Emerging · Emerging topic under active research

Abstract (original English)

Objective To assess the feasibility of the entire micro fragmented adipose tissue knee injection procedure under local anesthesia. From the subcutaneous harvesting and microfragmentation process to the intrarticular knee injection. Methods A patient with bilateral knee osteoarthritis underwent adipose tissue harvesting and bilateral intra-articular micro fragmented adipose tissue knee injection under local anesthesia. Patient-related outcomes were collected before the procedure, 12 months, and 24 months follow-up. Womac, Koos, and VAS were recorded. Results The visual analog scale, KOOS questionnaire, and WOMAC score all improved in the 12- and 24-month follow-ups. Conclusion Adipose tissue harvesting and micro fragmented adipose tissue knee injection are procedures that can be performed under local anesthesia and have good patient report outcomes. Level of Evidence IV; Therapeutic Study.

Evidence level

Evidence from laboratory and animal studies provides groundwork for understanding mechanisms and potential before human studies continue.

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