Level D· Preclinical EvidenceLaboratory Study

Regenerative Scalp Preparation With Stromal Vascular Fraction and Platelet-Rich Fibrin Prior to Hair Transplantation in Lichen Planus: A Case Report.

Bozorg Savoji P., Mirbahari SN., Rafiee S., Fakhim T., Nilforoushzadeh MA.

Laboratory Study on Hair Loss, published in Clin Case Rep (2026) — summary generated from the PubMed abstract.

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Study type
Laboratory Study
Journal
Clin Case Rep (2026)
Country
England
Reported sample size
PMID
42006542
DOI
10.1002/ccr3.72084

Abstract (original English)

Lichen planus (LP) is a chronic inflammatory scalp disorder that can lead to cicatricial alopecia, making it challenging for hair transplantation. This case report describes a 26-year-old female with LP who underwent scalp preparation using SVF and PRF before hair transplantation. SVF was administered 6 weeks prior, followed by PRF 4 weeks before the procedure to enhance scalp vascularization and reduce inflammation. After 1 year of follow-up, significant graft survival and improved scalp condition were observed without major complications. This report highlights the potential of SVF and PRF in optimizing hair transplantation outcomes for patients with LP.

What this study does not prove

  • This study does not prove SVF is an approved treatment or a replacement for standard care.
  • This is preclinical work; animal or laboratory results cannot be applied to humans.

Evidence level

Evidence comes from animal or laboratory studies and has not been confirmed in humans.

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