Research database
SVF Research Library
Search 52,792 real PubMed studies on SVF and adipose-derived stem cells — 11 matching records.
11 results — page 1 of 1
- Level DNarrative ReviewEurope PMC
Adipose tissue dysfunction disrupts metabolic homeostasis: mechanisms linking fat dysregulation to disease
Narrative Review on Type 2 Diabetes, published in Front Endocrinol (Lausanne) (2025) — summary generated from the PubMed abstract.
- 2025
Front Endocrinol (Lausanne)13 citations - Level CProspective StudyPubMed
[Metabolic dysregulation in adipose tissue macrophages and its link to obesity and obesity with type 2 diabetes based on single-cell transcriptome sequencing].
Prospective Study on Type 2 Diabetes, published in Zhonghua Yi Xue Za Zhi (2025) — summary generated from the PubMed abstract.
- 2025
Zhonghua Yi Xue Za Zhi - Level DAnimal StudyEurope PMC
Dysregulation of macrophage PEPD in obesity determines adipose tissue fibro-inflammation and insulin resistance
Animal Study on Type 2 Diabetes, Chronic Inflammation, published in Nat Metab (2022) — summary generated from the PubMed abstract.
- 2022
Nat Metab42 citations - Level DAnimal StudyEurope PMC
GPx3 dysregulation impacts adipose tissue insulin receptor expression and sensitivity
Animal Study on Type 2 Diabetes, published in JCI Insight (2020) — summary generated from the PubMed abstract.
- 2020
JCI Insight43 citations - Level DAnimal StudyPubMed
Human adipose tissue mesenchymal stem cells as a novel treatment modality for correcting obesity induced metabolic dysregulation.
Animal Study on Type 2 Diabetes, published in Int J Obes (Lond) (2019) — summary generated from the PubMed abstract.
- 2019
Int J Obes (Lond) - Level DAnimal StudyEurope PMC
Dysregulation of Amyloid Precursor Protein Impairs Adipose Tissue Mitochondrial Function and Promotes Obesity
Animal Study on Type 2 Diabetes, published in Nat Metab (2019) — summary generated from the PubMed abstract.
- 2019
Nat Metab57 citations - Level DAnimal StudyEurope PMC
Adipocyte-Specific Hypoxia-Inducible Factor 2α Deficiency Exacerbates Obesity-Induced Brown Adipose Tissue Dysfunction and Metabolic Dysregulation
Animal Study on Type 2 Diabetes, published in Mol Cell Biol (2016) — summary generated from the PubMed abstract.
- 2016
Mol Cell Biol69 citations - Level DNarrative ReviewPubMed
Changes in adipose tissue cellular composition during obesity and aging as a cause of metabolic dysregulation.
Narrative Review on Type 2 Diabetes, published in Exp Gerontol (2016) — summary generated from the PubMed abstract.
- 2016
Exp Gerontol60 citations - Level CProspective StudyPubMed
Cell-specific dysregulation of microRNA expression in obese white adipose tissue.
Prospective Study, published in J Clin Endocrinol Metab (2014) — summary generated from the PubMed abstract.
- 2014
J Clin Endocrinol Metab49 citations - Level CProspective StudyEurope PMC
Adipose tissue dysregulation and reduced insulin sensitivity in non-obese individuals with enlarged abdominal adipose cells
Prospective Study on Type 2 Diabetes, published in Diabetol Metab Syndr (2012) — summary generated from the PubMed abstract.
- 2012
Diabetol Metab Syndr81 citations - Level CProspective StudyEurope PMC
Adipose tissue dysregulation in patients with metabolic syndrome
Prospective Study on Type 2 Diabetes, published in J Clin Endocrinol Metab (2011) — summary generated from the PubMed abstract.
- 2011
J Clin Endocrinol Metab141 citations
In-depth reviewed studies (full Thai translation)
Evidence system- Level ARandomized Controlled Trial
Cell-based versus corticosteroid injections for knee pain in osteoarthritis: a randomized phase 3 trial
A multicentre randomized trial in 480 knee osteoarthritis patients comparing SVF, BMAC and umbilical cord MSCs against corticosteroid injection. At 12 months no cell product outperformed the steroid control.
- 2023
- United States
- n = 480
- Level AMeta-analysis
Intra-articular Injection of Autologous Adipose-Derived Stem Cells or Stromal Vascular Fractions: Are They Effective for Patients With Knee Osteoarthritis? A Systematic Review With Meta-analysis of Randomized Controlled Trials
Pooled five RCTs comparing ADSC/SVF injection with placebo or hyaluronic acid, finding significant pain and function improvement at 6 and 12 months.
- 2023
- South Korea
- Level AMeta-analysis
Rapid-acting pain relief in knee osteoarthritis: autologous-cultured adipose-derived mesenchymal stem cells outperform stromal vascular fraction: a systematic review and meta-analysis
Analysed 31 studies with 1,406 patients: cultured ADMSCs reduced pain from month 3, whereas SVF reached significance only at 12 months.
- 2024
- South Korea
- n = 1406