Research database
SVF Research Library
Search 52,792 real PubMed studies on SVF and adipose-derived stem cells — 28 matching records.
28 results — page 1 of 2
- Level DNarrative ReviewEurope PMC
Apoptotic mesenchymal stem cells and their secreted apoptotic extracellular vesicles: therapeutic applications and mechanisms
Narrative Review on Chronic Inflammation, Immune Modulation, published in Stem Cell Res Ther (2025) — summary generated from the PubMed abstract.
- 2025
Stem Cell Res Ther16 citations - Level AMeta-analysisEurope PMC
Mesenchymal stem cells-derived small extracellular vesicles and apoptotic extracellular vesicles for wound healing and skin regeneration: a systematic review and meta-analysis of preclinical studies
Meta-analysis on Chronic Wound, Scar, published in J Transl Med (2025) — summary generated from the PubMed abstract.
- 2025
J Transl Med12 citations - Level CProspective StudyPubMed
Mesenchymal stem cell-derived apoptotic vesicles regulate irritable bowel syndrome in mice via the 5-HT brain-gut axis.
Prospective Study, published in Stem Cell Res Ther (2025) — summary generated from the PubMed abstract.
- 2025
Stem Cell Res Ther3 citations - Level DAnimal StudyPubMed
Apoptotic extracellular vesicles from peripancreatic adipose-derived mesenchymal stem cells ameliorate severe acute pancreatitis through the transcription factor EB-mediated autophagy-lysosomal pathway: an experimental s
Animal Study on Systemic / IV, published in Int J Surg (2025) — summary generated from the PubMed abstract.
- 2025
Int J Surg1 citations - Level DAnimal StudyEurope PMC
Mesenchymal stem cell-derived apoptotic extracellular vesicles loaded with Prussian blue nanoparticles attenuate severe acute pancreatitis via neutrophil extracellular traps resolution and acinar-ductal metaplasia promot
Animal Study on Chronic Inflammation, published in J Nanobiotechnology (2025) — summary generated from the PubMed abstract.
- 2025
J Nanobiotechnology1 citations - Level DLaboratory StudyPubMed
Apoptotic extracellular vesicles derived from hypoxia-preconditioned mesenchymal stem cells within a modified gelatine hydrogel promote osteochondral regeneration by enhancing stem cell activity and regulating immunity.
Laboratory Study on Cartilage Damage, Immune Modulation, published in J Nanobiotechnology (2024) — summary generated from the PubMed abstract.
- 2024
J Nanobiotechnology41 citations - Level DAnimal StudyEurope PMC
Functional diversity of apoptotic vesicle subpopulations from bone marrow mesenchymal stem cells in tissue regeneration
Animal Study on Chronic Wound, published in J Extracell Vesicles (2024) — summary generated from the PubMed abstract.
- 2024
J Extracell Vesicles27 citations - Level DAnimal StudyEurope PMC
Therapeutic role of mesenchymal stem cells and platelet-rich plasma on skin burn healing and rejuvenation: A focus on scar regulation, oxido-inflammatory stress and apoptotic mechanisms
Animal Study on Chronic Wound, Burns, Scar, Chronic Inflammation, published in Heliyon (2023) — summary generated from the PubMed abstract.
- 2023
Heliyon26 citations - Level CProspective StudyPubMed
Adipose-derived mesenchymal stem cells cultured in serum-free medium attenuate acute contrast-induced nephropathy by exerting anti-apoptotic effects.
Prospective Study on Chronic Kidney Disease, Acute Kidney Injury, Chronic Inflammation, published in Stem Cell Res Ther (2023) — summary generated from the PubMed abstract.
- 2023
Stem Cell Res Ther5 citations - Level BClinical TrialPubMed
Clinical-grade human skin-derived ABCB5+ mesenchymal stromal cells exert anti-apoptotic and anti-inflammatory effects in vitro and modulate mRNA expression in a cisplatin-induced kidney injury murine model.
Clinical Trial on Chronic Kidney Disease, Acute Kidney Injury, Chronic Inflammation, Immune Modulation, published in Front Immunol (2023) — summary generated from the PubMed abstract.
- 2023
Front Immunol3 citations - Level DAnimal StudyEurope PMC
Efficacy of mesenchymal stem cells cultured low oxygen tension ameliorates apoptotic inhibitors, viability, and differentiation of ovarian tissue: A study in a rat model with ovarian failure
Animal Study on Hair & Scalp, published in F1000Res (2023) — summary generated from the PubMed abstract.
- 2023
F1000Res2 citations - Level DAnimal StudyPubMed
Apoptotic bodies extracted from adipose mesenchymal stem cells carry microRNA-21-5p to induce M2 polarization of macrophages and augment skin wound healing by targeting KLF6.
Animal Study on Chronic Wound, Burns, published in Burns (2022) — summary generated from the PubMed abstract.
- 2022
Burns44 citations - Level DAnimal StudyEurope PMC
Macrophage-derived apoptotic vesicles regulate fate commitment of mesenchymal stem cells via miR155
Animal Study on Immune Modulation, published in Stem Cell Res Ther (2022) — summary generated from the PubMed abstract.
- 2022
Stem Cell Res Ther25 citations - Level CProspective StudyPubMed
Mesenchymal stem cells combined with liraglutide relieve acute lung injury through apoptotic signaling restrained by PKA/β-catenin.
Prospective Study on Chronic Inflammation, published in Stem Cell Res Ther (2020) — summary generated from the PubMed abstract.
- 2020
Stem Cell Res Ther12 citations - Level DLaboratory StudyPubMed
Investigating The Alterations of Oxidative Stress Status, Antioxidant Defense Mechanisms, MAP Kinase and Mitochondrial Apoptotic Pathway in Adipose-Derived Mesenchymal Stem Cells from STZ Diabetic Rats.
Laboratory Study on Systemic / IV, published in Cell J (2020) — summary generated from the PubMed abstract.
- 2020
Cell J9 citations - Level DAnimal StudyEurope PMC
Melatonin suppresses ER stress-dependent proapoptotic effects via AMPK in bone mesenchymal stem cells during mitochondrial oxidative damage
Animal Study, published in Stem Cell Res Ther (2020) — summary generated from the PubMed abstract.
- 2020
Stem Cell Res Ther38 citations - Level DAnimal StudyEurope PMC
Apoptotic bodies derived from mesenchymal stem cells promote cutaneous wound healing via regulating the functions of macrophages
Animal Study on Chronic Wound, Chronic Inflammation, published in Stem Cell Res Ther (2020) — summary generated from the PubMed abstract.
- 2020
Stem Cell Res Ther143 citations - Level DAnimal StudyPubMed
Evaluation of Anti-Inflammatory and Antiapoptotic Effects of Bone Marrow and Adipose-Derived Mesenchymal Stem Cells in Acute Alkaline Corneal Burn.
Animal Study with a reported sample of 8 on Chronic Wound, Chronic Inflammation, published in J Ocul Pharmacol Ther (2020) — summary generated from the PubMed abstract.
- 2020
- n = 8
J Ocul Pharmacol Ther11 citations - Level DLaboratory StudyEurope PMC
Targeting of CD133+ Cancer Stem Cells by Mesenchymal Stem Cell Expressing TRAIL Reveals a Prospective Role of Apoptotic Gene Regulation in Non-Small Cell Lung Cancer
Laboratory Study, published in Cancers (Basel) (2019) — summary generated from the PubMed abstract.
- 2019
Cancers (Basel)23 citations - Level BClinical TrialPubMed
Anti-apoptotic effects of adipose-derived adherent stromal cells in mesenchymal stem cells exposed to oxidative stress.
Clinical Trial on Cardiovascular Disease, published in Cell Biochem Funct (2018) — summary generated from the PubMed abstract.
- 2018
Cell Biochem Funct6 citations - Level DAnimal StudyPubMed
Effect of efferocytosis of apoptotic mesenchymal stem cells (MSCs) on C57BL/6 peritoneal macrophages function.
Animal Study on Chronic Inflammation, published in Life Sci (2018) — summary generated from the PubMed abstract.
- 2018
Life Sci44 citations - Level DAnimal StudyPubMed
Pro-apoptotic and Growth-inhibitory Effect of IFN-β-Overexpressing Canine Adipose Tissue-derived Mesenchymal Stem Cells Against Melanoma Cells.
Animal Study, published in Anticancer Res (2015) — summary generated from the PubMed abstract.
- 2015
Anticancer Res - Level DLaboratory StudyPubMed
Human adipose-derived mesenchymal stem cells repair cisplatin-induced acute kidney injury through antiapoptotic pathways.
Laboratory Study on Chronic Kidney Disease, Acute Kidney Injury, published in Exp Ther Med (2015) — summary generated from the PubMed abstract.
- 2015
Exp Ther Med38 citations - Level DAnimal StudyPubMed
Additional benefit of combined therapy with melatonin and apoptotic adipose-derived mesenchymal stem cell against sepsis-induced kidney injury.
Animal Study with a reported sample of 65 on Acute Kidney Injury, published in J Pineal Res (2014) — summary generated from the PubMed abstract.
- 2014
- n = 65
J Pineal Res134 citations
In-depth reviewed studies (full Thai translation)
Evidence system- Level ARandomized Controlled Trial
Cell-based versus corticosteroid injections for knee pain in osteoarthritis: a randomized phase 3 trial
A multicentre randomized trial in 480 knee osteoarthritis patients comparing SVF, BMAC and umbilical cord MSCs against corticosteroid injection. At 12 months no cell product outperformed the steroid control.
- 2023
- United States
- n = 480
- Level AMeta-analysis
Intra-articular Injection of Autologous Adipose-Derived Stem Cells or Stromal Vascular Fractions: Are They Effective for Patients With Knee Osteoarthritis? A Systematic Review With Meta-analysis of Randomized Controlled Trials
Pooled five RCTs comparing ADSC/SVF injection with placebo or hyaluronic acid, finding significant pain and function improvement at 6 and 12 months.
- 2023
- South Korea
- Level AMeta-analysis
Rapid-acting pain relief in knee osteoarthritis: autologous-cultured adipose-derived mesenchymal stem cells outperform stromal vascular fraction: a systematic review and meta-analysis
Analysed 31 studies with 1,406 patients: cultured ADMSCs reduced pain from month 3, whereas SVF reached significance only at 12 months.
- 2024
- South Korea
- n = 1406