Research database
SVF Research Library
Search 52,792 real PubMed studies on SVF and adipose-derived stem cells — 23 matching records.
23 results — page 1 of 1
- Level DLaboratory StudyEurope PMC
Caspase-1/11 deficiency and cold exposure enhance the anti-tumor activity of brown adipose tissue secretome against breast cancer cells
Laboratory Study on Chronic Wound, published in Cancer Metab (2026) — summary generated from the PubMed abstract.
- 2026
Cancer Metab - Level DLaboratory StudyEurope PMC
Myeloid GHSR Deficiency Protects Against Thermogenic Impairment in Aging Through Immune Remodeling of Brown Adipose Tissue
Laboratory Study on Chronic Inflammation, published in Cells (2026) — summary generated from the PubMed abstract.
- 2026
Cells - Level DAnimal StudyPubMed
Superoxide dismutase 2 deficiency in mesenchymal stromal cells induces sympathetic denervation and functional impairment of brown adipose tissue.
Animal Study, published in Pathol Int (2025) — summary generated from the PubMed abstract.
- 2025
Pathol Int - Level DAnimal StudyEurope PMC
Endothelial SIRT3 deficiency predisposes brown adipose tissue to whitening in diet-induced obesity
Animal Study on Type 2 Diabetes, published in Int J Biol Sci (2025) — summary generated from the PubMed abstract.
- 2025
Int J Biol Sci2 citations - Level DAnimal StudyEurope PMC
Pde5a deficiency prevents diet-induced obesity via adipose cAMP-PKA activation enhancing fat browning
Animal Study on Systemic / IV, published in Mol Metab (2025) — summary generated from the PubMed abstract.
- 2025
Mol Metab2 citations - Level DAnimal StudyEurope PMC
Brown adipose tissue CoQ deficiency activates the integrated stress response and FGF21-dependent mitohormesis
Animal Study, published in EMBO J (2024) — summary generated from the PubMed abstract.
- 2024
EMBO J10 citations - Level DAnimal StudyEurope PMC
βAR-mTOR-lipin1 pathway mediates PKA-RIIβ deficiency-induced adipose browning
Animal Study, published in Theranostics (2024) — summary generated from the PubMed abstract.
- 2024
Theranostics7 citations - Level DAnimal StudyEurope PMC
GRAF1 deficiency leads to defective brown adipose tissue differentiation and thermogenic response
Animal Study, published in Sci Rep (2024) — summary generated from the PubMed abstract.
- 2024
Sci Rep1 citations - Level DAnimal StudyPubMed
Hepcidin deficiency in mice impairs white adipose tissue browning possibly due to a defect in de novo adipogenesis.
Animal Study, published in Sci Rep (2023) — summary generated from the PubMed abstract.
- 2023
Sci Rep6 citations - Level DAnimal StudyPubMed
HDAC11 deficiency resists obesity by converting adipose-derived stem cells into brown adipocyte-like cells.
Animal Study on Type 2 Diabetes, published in Int J Biol Macromol (2023) — summary generated from the PubMed abstract.
- 2023
Int J Biol Macromol7 citations - Level DAnimal StudyEurope PMC
Brown adipose TRX2 deficiency activates mtDNA-NLRP3 to impair thermogenesis and protect against diet-induced insulin resistance
Animal Study on Type 2 Diabetes, published in J Clin Invest (2022) — summary generated from the PubMed abstract.
- 2022
J Clin Invest45 citations - Level DAnimal StudyEurope PMC
Differing impact of phosphoglycerate mutase 1-deficiency on brown and white adipose tissue
Animal Study on Systemic / IV, published in iScience (2022) — summary generated from the PubMed abstract.
- 2022
iScience4 citations - Level DAnimal StudyEurope PMC
TFEB deficiency attenuates mitochondrial degradation upon brown adipose tissue whitening at thermoneutrality
Animal Study on Systemic / IV, published in Mol Metab (2021) — summary generated from the PubMed abstract.
- 2021
Mol Metab27 citations - Level DLaboratory StudyEurope PMC
Catalase deficiency facilitates the shuttling of free fatty acid to brown adipose tissue through lipolysis mediated by ROS during sustained fasting
Laboratory Study, published in Cell Biosci (2021) — summary generated from the PubMed abstract.
- 2021
Cell Biosci19 citations - Level DAnimal StudyPubMed
Deficiency in interleukin-18 promotes differentiation of brown adipose tissue resulting in fat accumulation despite dyslipidemia.
Animal Study on Hip, Systemic / IV, published in J Transl Med (2018) — summary generated from the PubMed abstract.
- 2018
J Transl Med13 citations - Level DAnimal StudyPubMed
Egr1 deficiency induces browning of inguinal subcutaneous white adipose tissue in mice.
Animal Study, published in Sci Rep (2017) — summary generated from the PubMed abstract.
- 2017
Sci Rep - Level CProspective StudyPubMed
Cdkn2a deficiency promotes adipose tissue browning.
Prospective Study on Type 2 Diabetes, published in Mol Metab (2017) — summary generated from the PubMed abstract.
- 2017
Mol Metab35 citations - Level DAnimal StudyEurope PMC
Adipocyte-Specific Hypoxia-Inducible Factor 2α Deficiency Exacerbates Obesity-Induced Brown Adipose Tissue Dysfunction and Metabolic Dysregulation
Animal Study on Type 2 Diabetes, published in Mol Cell Biol (2016) — summary generated from the PubMed abstract.
- 2016
Mol Cell Biol69 citations - Level DAnimal StudyEurope PMC
IEX-1 deficiency induces browning of white adipose tissue and resists diet-induced obesity
Animal Study on Type 2 Diabetes, Chronic Inflammation, published in Sci Rep (2016) — summary generated from the PubMed abstract.
- 2016
Sci Rep19 citations - Level DAnimal StudyEurope PMC
Seipin deficiency alters brown adipose tissue thermogenesis and insulin sensitivity in a non-cell autonomous mode
Animal Study on Type 2 Diabetes, published in Sci Rep (2016) — summary generated from the PubMed abstract.
- 2016
Sci Rep19 citations - Level DAnimal StudyEurope PMC
Brown Adipose YY1 Deficiency Activates Expression of Secreted Proteins Linked to Energy Expenditure and Prevents Diet-Induced Obesity
Animal Study, published in Mol Cell Biol (2015) — summary generated from the PubMed abstract.
- 2015
Mol Cell Biol36 citations - Level DAnimal StudyPubMed
Adipose-specific lipoprotein lipase deficiency more profoundly affects brown than white fat biology.
Animal Study, published in J Biol Chem (2013) — summary generated from the PubMed abstract.
- 2013
J Biol Chem - Level DAnimal StudyEurope PMC
Deficiency of growth differentiation factor 3 protects against diet-induced obesity by selectively acting on white adipose
Animal Study, published in Mol Endocrinol (2009) — summary generated from the PubMed abstract.
- 2009
Mol Endocrinol49 citations
In-depth reviewed studies (full Thai translation)
Evidence system- Level ARandomized Controlled Trial
Cell-based versus corticosteroid injections for knee pain in osteoarthritis: a randomized phase 3 trial
A multicentre randomized trial in 480 knee osteoarthritis patients comparing SVF, BMAC and umbilical cord MSCs against corticosteroid injection. At 12 months no cell product outperformed the steroid control.
- 2023
- United States
- n = 480
- Level AMeta-analysis
Intra-articular Injection of Autologous Adipose-Derived Stem Cells or Stromal Vascular Fractions: Are They Effective for Patients With Knee Osteoarthritis? A Systematic Review With Meta-analysis of Randomized Controlled Trials
Pooled five RCTs comparing ADSC/SVF injection with placebo or hyaluronic acid, finding significant pain and function improvement at 6 and 12 months.
- 2023
- South Korea
- Level AMeta-analysis
Rapid-acting pain relief in knee osteoarthritis: autologous-cultured adipose-derived mesenchymal stem cells outperform stromal vascular fraction: a systematic review and meta-analysis
Analysed 31 studies with 1,406 patients: cultured ADMSCs reduced pain from month 3, whereas SVF reached significance only at 12 months.
- 2024
- South Korea
- n = 1406