Research database
SVF Research Library
Search 52,792 real PubMed studies on SVF and adipose-derived stem cells — 42 matching records.
42 results — page 1 of 2
- Level BRandomized Controlled TrialPubMed
Combination ex vivo regional gene therapy with sonic hedgehog and bone morphogenetic protein-2 does not enhance bone healing in critical size defects.
Randomized Controlled Trial, published in Connect Tissue Res (2026) — summary generated from the PubMed abstract.
- 2026
Connect Tissue Res - Level DAnimal StudyEurope PMC
Ex Vivo Regional Gene Therapy Compared to Recombinant BMP-2 for the Treatment of Critical-Size Bone Defects: An In Vivo Single-Cell RNA-Sequencing Study
Animal Study on Cartilage Damage, Chronic Inflammation, published in Bioengineering (Basel) (2025) — summary generated from the PubMed abstract.
- 2025
Bioengineering (Basel)2 citations - Level ASystematic ReviewEurope PMC
Milestones in Mandibular Bone Tissue Engineering: A Systematic Review of Large Animal Models and Critical-Sized Defects
Systematic Review, published in J Clin Med (2025) — summary generated from the PubMed abstract.
- 2025
J Clin Med10 citations - Level DNarrative ReviewEurope PMC
Promoting bone generation through the accordion technique in critical-sized bone defects: a review
Narrative Review, published in Int J Surg (2025) — summary generated from the PubMed abstract.
- 2025
Int J Surg - Level DAnimal StudyPubMed
Evaluation of adipose-derived stem cells (ASCS) exosome implantation and platelet-rich fibrin (PRF) on critical long bone defects in Sprague-Dawley rats.
Animal Study, published in Eur J Orthop Surg Traumatol (2024) — summary generated from the PubMed abstract.
- 2024
Eur J Orthop Surg Traumatol3 citations - Level DNarrative ReviewEurope PMC
Towards Stem Cell Therapy for Critical-Sized Segmental Bone Defects: Current Trends and Challenges on the Path to Clinical Translation
Narrative Review, published in J Funct Biomater (2024) — summary generated from the PubMed abstract.
- 2024
J Funct Biomater13 citations - Level DLaboratory StudyPubMed
Bone Regeneration of Rat Critical-Sized Calvarial Defects by the Combination of Photobiomodulation and Adipose-Derived Mesenchymal Stem Cells.
Laboratory Study, published in J Lasers Med Sci (2024) — summary generated from the PubMed abstract.
- 2024
J Lasers Med Sci4 citations - Level DAnimal StudyEurope PMC
Bone Morphogenetic Protein-2 Rapidly Heals Two Distinct Critical Sized Segmental Diaphyseal Bone Defects in a Porcine Model
Animal Study with a reported sample of 8 on Chronic Wound, published in Mil Med (2023) — summary generated from the PubMed abstract.
- 2023
- n = 8
Mil Med4 citations - Level DNarrative ReviewEurope PMC
The potential therapeutic role of extracellular vesicles in critical-size bone defects: Spring of cell-free regenerative medicine is coming
Narrative Review, published in Front Bioeng Biotechnol (2023) — summary generated from the PubMed abstract.
- 2023
Front Bioeng Biotechnol9 citations - Level DNarrative ReviewEurope PMC
Functional Approaches in Promoting Vascularization and Angiogenesis in Bone Critical-Sized Defects via Delivery of Cells, Growth Factors, Drugs, and Particles
Narrative Review, published in J Funct Biomater (2023) — summary generated from the PubMed abstract.
- 2023
J Funct Biomater17 citations - Level DNarrative ReviewEurope PMC
Regeneration of Critical-Sized Mandibular Defects Using 3D-Printed Composite Scaffolds: A Quantitative Evaluation of New Bone Formation in In Vivo Studies
Narrative Review on Face & Skin, published in Adv Healthc Mater (2023) — summary generated from the PubMed abstract.
- 2023
Adv Healthc Mater21 citations - Level DAnimal StudyPubMed
Point-of-care treatment of geometrically complex midfacial critical-sized bone defects with 3D-Printed scaffolds and autologous stromal vascular fraction.
Animal Study on Face & Skin, published in Biomaterials (2022) — summary generated from the PubMed abstract.
- 2022
Biomaterials17 citations - Level DAnimal StudyPubMed
Different Protocols of Combined Application of Photobiomodulation In Vitro and In Vivo Plus Adipose-Derived Stem Cells Improve the Healing of Bones in Critical Size Defects in Rat Models.
Animal Study, published in J Lasers Med Sci (2022) — summary generated from the PubMed abstract.
- 2022
J Lasers Med Sci8 citations - Level DAnimal StudyEurope PMC
Injectable nanoporous microgels generate vascularized constructs and support bone regeneration in critical-sized defects
Animal Study on Face & Skin, published in Sci Rep (2022) — summary generated from the PubMed abstract.
- 2022
Sci Rep25 citations - Level DNarrative ReviewEurope PMC
3D-Printing for Critical Sized Bone Defects: Current Concepts and Future Directions
Narrative Review, published in Bioengineering (Basel) (2022) — summary generated from the PubMed abstract.
- 2022
Bioengineering (Basel)39 citations - Level DAnimal StudyEurope PMC
Repair of critical-size porcine craniofacial bone defects using a collagen-polycaprolactone composite biomaterial
Animal Study on Face & Skin, published in Biofabrication (2021) — summary generated from the PubMed abstract.
- 2021
Biofabrication24 citations - Level DNarrative ReviewEurope PMC
A Critical Review on the Design, Manufacturing and Assessment of the Bone Scaffold for Large Bone Defects
Narrative Review, published in Front Bioeng Biotechnol (2021) — summary generated from the PubMed abstract.
- 2021
Front Bioeng Biotechnol19 citations - Level DAnimal StudyPubMed
In situ production of pre-vascularized synthetic bone grafts for regenerating critical-sized defects in rabbits.
Animal Study, published in Acta Biomater (2020) — summary generated from the PubMed abstract.
- 2020
Acta Biomater27 citations - Level DAnimal StudyEurope PMC
The co-culture of ASCs and EPCs promotes vascularized bone regeneration in critical-sized bone defects of cranial bone in rats
Animal Study on Face & Skin, published in Stem Cell Res Ther (2020) — summary generated from the PubMed abstract.
- 2020
Stem Cell Res Ther23 citations - Level DAnimal StudyEurope PMC
miRNA-21 promotes osteogenesis via the PTEN/PI3K/Akt/HIF-1α pathway and enhances bone regeneration in critical size defects
Animal Study on Face & Skin, published in Stem Cell Res Ther (2019) — summary generated from the PubMed abstract.
- 2019
Stem Cell Res Ther157 citations - Level DAnimal StudyPubMed
The effect of combination therapy on critical-size bone defects using non-activated platelet-rich plasma and adipose-derived stem cells.
Animal Study on Face & Skin, published in Childs Nerv Syst (2019) — summary generated from the PubMed abstract.
- 2019
Childs Nerv Syst4 citations - Level DNarrative ReviewEurope PMC
Genetically Engineered-MSC Therapies for Non-unions, Delayed Unions and Critical-size Bone Defects
Narrative Review on Immune Modulation, published in Int J Mol Sci (2019) — summary generated from the PubMed abstract.
- 2019
Int J Mol Sci34 citations - Level DAnimal StudyPubMed
Transplantation of dedifferentiated fat cells combined with a biodegradable type I collagen-recombinant peptide scaffold for critical-size bone defects in rats.
Animal Study on Face & Skin, published in J Oral Sci (2019) — summary generated from the PubMed abstract.
- 2019
J Oral Sci18 citations - Level DAnimal StudyPubMed
Low power laser irradiation and human adipose-derived stem cell treatments promote bone regeneration in critical-sized calvarial defects in rats.
Animal Study, published in PLoS One (2018) — summary generated from the PubMed abstract.
- 2018
PLoS One30 citations
In-depth reviewed studies (full Thai translation)
Evidence system- Level ARandomized Controlled Trial
Cell-based versus corticosteroid injections for knee pain in osteoarthritis: a randomized phase 3 trial
A multicentre randomized trial in 480 knee osteoarthritis patients comparing SVF, BMAC and umbilical cord MSCs against corticosteroid injection. At 12 months no cell product outperformed the steroid control.
- 2023
- United States
- n = 480
- Level AMeta-analysis
Intra-articular Injection of Autologous Adipose-Derived Stem Cells or Stromal Vascular Fractions: Are They Effective for Patients With Knee Osteoarthritis? A Systematic Review With Meta-analysis of Randomized Controlled Trials
Pooled five RCTs comparing ADSC/SVF injection with placebo or hyaluronic acid, finding significant pain and function improvement at 6 and 12 months.
- 2023
- South Korea
- Level AMeta-analysis
Rapid-acting pain relief in knee osteoarthritis: autologous-cultured adipose-derived mesenchymal stem cells outperform stromal vascular fraction: a systematic review and meta-analysis
Analysed 31 studies with 1,406 patients: cultured ADMSCs reduced pain from month 3, whereas SVF reached significance only at 12 months.
- 2024
- South Korea
- n = 1406