Research database
SVF Research Library
Search 52,792 real PubMed studies on SVF and adipose-derived stem cells — 9 matching records.
9 results — page 1 of 1
- Level CProspective StudyPubMed
Free Fatty Acids from Type 2 Diabetes Mellitus Serum Remodel Mesenchymal Stem Cell Lipids, Hindering Differentiation into Primordial Germ Cells.
Prospective Study on Type 2 Diabetes, published in Appl Biochem Biotechnol (2022) — summary generated from the PubMed abstract.
- 2022
Appl Biochem Biotechnol - Level DNarrative ReviewEurope PMC
Physiologic and pathologic effects of dietary free fatty acids on cells of the joint
Narrative Review on Osteoarthritis, Chronic Inflammation, published in Ann N Y Acad Sci (2019) — summary generated from the PubMed abstract.
- 2019
Ann N Y Acad Sci36 citations - Level DLaboratory StudyPubMed
Expression of miR-199a-3p in human adipocytes is regulated by free fatty acids and adipokines.
Laboratory Study on Type 2 Diabetes, Chronic Inflammation, published in Mol Med Rep (2016) — summary generated from the PubMed abstract.
- 2016
Mol Med Rep36 citations - Level CProspective StudyPubMed
[Effect of free fatty acids on CYP19A1 (aromatase) gene expression in human adipose tissue stromal vascular fraction cells].
Prospective Study with a reported sample of 38, published in Przegl Lek (2016) — summary generated from the PubMed abstract.
- 2016
- n = 38
Przegl Lek - Level DAnimal StudyEurope PMC
Free fatty acids, lipopolysaccharide and IL-1α induce adipocyte manganese superoxide dismutase which is increased in visceral adipose tissues of obese rodents
Animal Study on Systemic / IV, published in PLoS One (2014) — summary generated from the PubMed abstract.
- 2014
PLoS One20 citations - Level BClinical TrialEurope PMC
Glucose-dependent insulinotropic polypeptide reduces fat-specific expression and activity of 11β-hydroxysteroid dehydrogenase type 1 and inhibits release of free fatty acids
Clinical Trial, published in Diabetes (2012) — summary generated from the PubMed abstract.
- 2012
Diabetes40 citations - Level DAnimal StudyPubMed
Diet-induced obesity alters the differentiation potential of stem cells isolated from bone marrow, adipose tissue and infrapatellar fat pad: the effects of free fatty acids.
Animal Study on Knee, Systemic / IV, published in Int J Obes (Lond) (2012) — summary generated from the PubMed abstract.
- 2012
Int J Obes (Lond)79 citations - Level DAnimal StudyPubMed
Adipocytes differentiated in vitro from rat mesenchymal stem cells lack essential free fatty acids compared to adult adipocytes.
Animal Study, published in Stem Cells Dev (2011) — summary generated from the PubMed abstract.
- 2011
Stem Cells Dev - Level DAnimal StudyPubMed
A paracrine loop between adipocytes and macrophages aggravates inflammatory changes: role of free fatty acids and tumor necrosis factor alpha.
Animal Study, published in Arterioscler Thromb Vasc Biol (2005) — summary generated from the PubMed abstract.
- 2005
Arterioscler Thromb Vasc Biol762 citations
In-depth reviewed studies (full Thai translation)
Evidence system- Level ARandomized Controlled Trial
Cell-based versus corticosteroid injections for knee pain in osteoarthritis: a randomized phase 3 trial
A multicentre randomized trial in 480 knee osteoarthritis patients comparing SVF, BMAC and umbilical cord MSCs against corticosteroid injection. At 12 months no cell product outperformed the steroid control.
- 2023
- United States
- n = 480
- Level AMeta-analysis
Intra-articular Injection of Autologous Adipose-Derived Stem Cells or Stromal Vascular Fractions: Are They Effective for Patients With Knee Osteoarthritis? A Systematic Review With Meta-analysis of Randomized Controlled Trials
Pooled five RCTs comparing ADSC/SVF injection with placebo or hyaluronic acid, finding significant pain and function improvement at 6 and 12 months.
- 2023
- South Korea
- Level AMeta-analysis
Rapid-acting pain relief in knee osteoarthritis: autologous-cultured adipose-derived mesenchymal stem cells outperform stromal vascular fraction: a systematic review and meta-analysis
Analysed 31 studies with 1,406 patients: cultured ADMSCs reduced pain from month 3, whereas SVF reached significance only at 12 months.
- 2024
- South Korea
- n = 1406