Research database
SVF Research Library
Search 52,792 real PubMed studies on SVF and adipose-derived stem cells — 112 matching records.
112 results — page 1 of 5
- Level DAnimal StudyPubMed
Asprosin-driven metabolic-epigenetic rewiring attenuates mesenchymal stem cell senescence with therapeutic benefits for infarcted hearts.
Animal Study on Cardiovascular Disease, published in J Adv Res (2026) — summary generated from the PubMed abstract.
- 2026
J Adv Res - Level CProspective StudyPubMed
Adipose-derived mesenchymal stem cell exosomes enhance diabetic wound healing via the amelioration of fibroblast senescence through the SMARCAL1-Drp1 signaling pathway.
Prospective Study on Diabetic Foot, Chronic Wound, published in Biochim Biophys Acta Mol Basis Dis (2026) — summary generated from the PubMed abstract.
- 2026
Biochim Biophys Acta Mol Basis Dis - Level DLaboratory StudyPubMed
Senescence profiling and biomarker identification in cell product based on adipose tissue-derived mesenchymal stromal cells.
Laboratory Study on Immune Modulation, published in Stem Cells Transl Med (2026) — summary generated from the PubMed abstract.
- 2026
Stem Cells Transl Med - Level DLaboratory StudyEurope PMC
Phenotypic alterations and PI3K-AKT pathway regulation in senescence of human tonsil mesenchymal stem cells
Laboratory Study, published in Stem Cell Res Ther (2026) — summary generated from the PubMed abstract.
- 2026
Stem Cell Res Ther - Level BClinical TrialEurope PMC
Research progress of mesenchymal stem cells/stromal cells and their derivatives against cell senescence in the treatment of osteoarthritis
Clinical Trial on Osteoarthritis, Chronic Inflammation, published in Ann Med (2026) — summary generated from the PubMed abstract.
- 2026
Ann Med - Level DLaboratory StudyEurope PMC
Exercise rejuvenates bone marrow mesenchymal stem cells associated with the inhibition of inflammatory factors and senescence-related factors
Laboratory Study, published in Biochem Biophys Rep (2026) — summary generated from the PubMed abstract.
- 2026
Biochem Biophys Rep - Level DLaboratory StudyPubMed
Melatonin and Coenzyme Q10 mitigate Senescence in Human Adipose-Derived Mesenchymal Stem Cells by Restoring Mitophagy and Mitochondrial Proteostasis.
Laboratory Study, published in PLoS One (2026) — summary generated from the PubMed abstract.
- 2026
PLoS One - Level DLaboratory StudyEurope PMC
LncRNA NEAT1-206 regulates autophagy of human umbilical cord mesenchymal stem cells through the WNT5A/Ca 2+ signaling pathway under senescence stress
Laboratory Study, published in Noncoding RNA Res (2025) — summary generated from the PubMed abstract.
- 2025
Noncoding RNA Res1 citations - Level DLaboratory StudyEurope PMC
Combination Therapy of Losartan and Fisetin Reduces Senescence and Enhances Osteogenesis in Human Bone Marrow-Derived Mesenchymal Stem Cells
Laboratory Study, published in J Tissue Eng Regen Med (2025) — summary generated from the PubMed abstract.
- 2025
J Tissue Eng Regen Med2 citations - Level DAnimal StudyPubMed
Reduced NRF2/Mfn2 activity promotes endoplasmic reticulum stress and senescence in adipose-derived mesenchymal stem cells in hypertrophic obese mice.
Animal Study on Type 2 Diabetes, published in World J Stem Cells (2025) — summary generated from the PubMed abstract.
- 2025
World J Stem Cells1 citations - Level DLaboratory StudyEurope PMC
Umbilical cord mesenchymal stem cell exosomal miR-143-3p delays endothelial cell senescence through targeting COX-2
Laboratory Study, published in PLoS One (2025) — summary generated from the PubMed abstract.
- 2025
PLoS One2 citations - Level DNarrative ReviewEurope PMC
Mechanisms and therapeutic strategies linking mesenchymal stem cells senescence to osteoporosis
Narrative Review on Chronic Inflammation, published in Front Endocrinol (Lausanne) (2025) — summary generated from the PubMed abstract.
- 2025
Front Endocrinol (Lausanne)10 citations - Level DLaboratory StudyPubMed
Aging Adipose-Derived Mesenchymal Stem Cells, Cultured on a Native Young Extracellular Matrix, Are Protected From Senescence and Apoptosis Along With Increased Expression of HLA-DR and CD74 Associated With PI3K Signaling
Laboratory Study, published in Aging Cell (2025) — summary generated from the PubMed abstract.
- 2025
Aging Cell - Level CProspective StudyPubMed
Acute myeloid leukemia cells induce senescence and adipogenic differentiation of mesenchymal stem cells in a tumor-supportive microenvironment at the same time.
Prospective Study, published in Cell Signal (2025) — summary generated from the PubMed abstract.
- 2025
Cell Signal - Level DLaboratory StudyEurope PMC
FN9-10ELP, an ECM-Mimetic Fusion Protein, Protects Human Mesenchymal Stem Cells from Etoposide-Induced Senescence
Laboratory Study, published in Int J Mol Sci (2025) — summary generated from the PubMed abstract.
- 2025
Int J Mol Sci - Level DLaboratory StudyPubMed
Urolithin A Alleviates Doxorubicin-Induced Senescence in Mesenchymal Stem Cells.
Laboratory Study, published in Int J Mol Sci (2025) — summary generated from the PubMed abstract.
- 2025
Int J Mol Sci - Level DAnimal StudyPubMed
Curcumin controls the senescence of adipose-derived mesenchymal stem cells via the FoxO3/autophagy signaling pathway to enhance joint homeostasis for osteoarthritis therapy.
Animal Study on Osteoarthritis, Cartilage Damage, Meniscus Injury, Chronic Inflammation, published in Stem Cell Res Ther (2025) — summary generated from the PubMed abstract.
- 2025
Stem Cell Res Ther5 citations - Level DAnimal StudyEurope PMC
Comprehensive bulk and single-cell RNA sequencing uncovers senescence-associated biomarkers in therapeutic mesenchymal stem cells
Animal Study, published in Sci Rep (2025) — summary generated from the PubMed abstract.
- 2025
Sci Rep - Level DLaboratory StudyPubMed
Insights into mitofusin-2 and endoplasmic reticulum stress regulation in adipose-derived mesenchymal stem cells senescence.
Laboratory Study on Type 2 Diabetes, published in World J Stem Cells (2025) — summary generated from the PubMed abstract.
- 2025
World J Stem Cells - Level DAnimal StudyPubMed
Mesenchymal stem cell-derived extracellular vesicles relieve endothelial cell senescence via recovering CTRP9 upon repressing miR-674-5p in atherosclerosis.
Animal Study, published in Regen Ther (2024) — summary generated from the PubMed abstract.
- 2024
Regen Ther7 citations - Level DLaboratory StudyPubMed
Ohwia caudata aqueous extract attenuates senescence in aging adipose-derived mesenchymal stem cells.
Laboratory Study, published in Heliyon (2024) — summary generated from the PubMed abstract.
- 2024
Heliyon5 citations - Level DAnimal StudyPubMed
Extracellular Vesicles Derived from H 2 O 2 -Stimulated Adipose-Derived Stem Cells Alleviate Senescence in Diabetic Bone Marrow Mesenchymal Stem Cells and Restore Their Osteogenic Capacity.
Animal Study on Systemic / IV, published in Drug Des Devel Ther (2024) — summary generated from the PubMed abstract.
- 2024
Drug Des Devel Ther6 citations - Level DNarrative ReviewEurope PMC
Role of Mesenchymal Stem/Stromal Cells (MSCs) and MSC-Derived Extracellular Vesicles (EVs) in Prevention of Telomere Length Shortening, Cellular Senescence, and Accelerated Biological Aging
Narrative Review, published in Bioengineering (Basel) (2024) — summary generated from the PubMed abstract.
- 2024
Bioengineering (Basel)9 citations - Level DLaboratory StudyEurope PMC
MiR-34a-HK1 signal axis retards bone marrow mesenchymal stem cell senescence via ameliorating glycolytic metabolism
Laboratory Study, published in Stem Cell Res Ther (2024) — summary generated from the PubMed abstract.
- 2024
Stem Cell Res Ther6 citations
In-depth reviewed studies (full Thai translation)
Evidence system- Level ARandomized Controlled Trial
Cell-based versus corticosteroid injections for knee pain in osteoarthritis: a randomized phase 3 trial
A multicentre randomized trial in 480 knee osteoarthritis patients comparing SVF, BMAC and umbilical cord MSCs against corticosteroid injection. At 12 months no cell product outperformed the steroid control.
- 2023
- United States
- n = 480
- Level AMeta-analysis
Intra-articular Injection of Autologous Adipose-Derived Stem Cells or Stromal Vascular Fractions: Are They Effective for Patients With Knee Osteoarthritis? A Systematic Review With Meta-analysis of Randomized Controlled Trials
Pooled five RCTs comparing ADSC/SVF injection with placebo or hyaluronic acid, finding significant pain and function improvement at 6 and 12 months.
- 2023
- South Korea
- Level AMeta-analysis
Rapid-acting pain relief in knee osteoarthritis: autologous-cultured adipose-derived mesenchymal stem cells outperform stromal vascular fraction: a systematic review and meta-analysis
Analysed 31 studies with 1,406 patients: cultured ADMSCs reduced pain from month 3, whereas SVF reached significance only at 12 months.
- 2024
- South Korea
- n = 1406