Research database
SVF Research Library
Search 52,792 real PubMed studies on SVF and adipose-derived stem cells — 93 matching records.
93 results — page 1 of 4
- Level DNarrative ReviewEurope PMC
Intervertebral disc progenitor cells: roles in regeneration and disease
Narrative Review on Disc Degeneration, published in Stem Cell Res Ther (2026) — summary generated from the PubMed abstract.
- 2026
Stem Cell Res Ther - Level DNarrative ReviewEurope PMC
Targeting ferroptosis to enhance the efficacy of mesenchymal stem cell-based treatments for intervertebral disc degeneration
Narrative Review on Disc Degeneration, published in Int J Biol Sci (2025) — summary generated from the PubMed abstract.
- 2025
Int J Biol Sci15 citations - Level DNarrative ReviewEurope PMC
Stem cell therapy for intervertebral disc degeneration: Clinical progress with exosomes and gene vectors
Narrative Review on Back Pain, Disc Degeneration, Immune Modulation, published in World J Stem Cells (2025) — summary generated from the PubMed abstract.
- 2025
World J Stem Cells6 citations - Level DNarrative ReviewEurope PMC
Exploring extracellular vesicles as novel therapeutic agents for intervertebral disc degeneration: delivery, applications, and mechanisms
Narrative Review on Back Pain, Disc Degeneration, published in Stem Cell Res Ther (2025) — summary generated from the PubMed abstract.
- 2025
Stem Cell Res Ther2 citations - Level DAnimal StudyEurope PMC
Bone mesenchymal stem cells based on matric hydrogels attenuate intervertebral disc degeneration by suppressing oxidative stress-induced ferroptosis
Animal Study on Back Pain, Disc Degeneration, published in Sci Rep (2025) — summary generated from the PubMed abstract.
- 2025
Sci Rep2 citations - Level DAnimal StudyPubMed
Investigating the regulation of the miR-199a-3p/TGF-β/Smad signaling pathway by BSHXF drug-containing serum combined with ADSCs for delaying intervertebral disc degeneration.
Animal Study on Back Pain, Disc Degeneration, Scar, published in Front Pharmacol (2025) — summary generated from the PubMed abstract.
- 2025
Front Pharmacol1 citations - Level DLaboratory StudyEurope PMC
Trends and emerging frontiers of mesenchymal stem cells in intervertebral disc degeneration: a bibliometric analysis (2000-2024)
Laboratory Study on Disc Degeneration, published in Front Med (Lausanne) (2025) — summary generated from the PubMed abstract.
- 2025
Front Med (Lausanne)1 citations - Level DNarrative ReviewEurope PMC
Nano-Drug Delivery System Targeting the Oxidative Stress Microenvironment: A Prospective Strategy for Intervertebral Disc Degeneration Treatment
Narrative Review on Back Pain, Disc Degeneration, published in Int J Nanomedicine (2025) — summary generated from the PubMed abstract.
- 2025
Int J Nanomedicine1 citations - Level DAnimal StudyEurope PMC
Comparative Regenerative Efficacy of PRP Combined with Chondrocytes or Mesenchymal Stem Cells for Intervertebral Disc Regeneration in a Rabbit Model
Animal Study on Back Pain, Disc Degeneration, published in Int J Mol Sci (2025) — summary generated from the PubMed abstract.
- 2025
Int J Mol Sci1 citations - Level BClinical TrialEurope PMC
Application of Endogenous Stem Cells in the Repair of Annulus Fibrosus Injury of Intervertebral Discs
Clinical Trial on Back Pain, Disc Degeneration, Chronic Inflammation, published in Stem Cells Int (2025) — summary generated from the PubMed abstract.
- 2025
Stem Cells Int1 citations - Level DAnimal StudyPubMed
Mechanically regulated differentiation of adipose-derived mesenchymal stem cells by PDA-functionalized injectable microgels towards intervertebral disc repair.
Animal Study on Disc Degeneration, published in Biomed Mater (2025) — summary generated from the PubMed abstract.
- 2025
Biomed Mater - Level DAnimal StudyPubMed
The regenerative potential of young versus senescent rabbit adipose-derived mesenchymal stem cells and their impact on the treatment of intervertebral disc degeneration.
Animal Study on Disc Degeneration, published in Spine J (2025) — summary generated from the PubMed abstract.
- 2025
Spine J - Level DNarrative ReviewEurope PMC
Stem cell-based strategies for intervertebral disc regeneration in degenerative microenvironments: challenges and solutions
Narrative Review on Back Pain, Disc Degeneration, Immune Modulation, published in Front Cell Dev Biol (2025) — summary generated from the PubMed abstract.
- 2025
Front Cell Dev Biol - Level DAnimal StudyEurope PMC
The most influential articles on stem cells in intervertebral disc degeneration
Animal Study on Disc Degeneration, published in BMC Musculoskelet Disord (2024) — summary generated from the PubMed abstract.
- 2024
BMC Musculoskelet Disord - Level ASystematic ReviewEurope PMC
Sirtuins in intervertebral disc degeneration: current understanding
Systematic Review on Back Pain, Disc Degeneration, Chronic Inflammation, published in Mol Med (2024) — summary generated from the PubMed abstract.
- 2024
Mol Med11 citations - Level DNarrative ReviewEurope PMC
The Emerging Roles of Nanocarrier Drug Delivery System in Treatment of Intervertebral Disc Degeneration-Current Knowledge, Hot Spots, Challenges and Future Perspectives
Narrative Review on Back Pain, Disc Degeneration, published in Drug Des Devel Ther (2024) — summary generated from the PubMed abstract.
- 2024
Drug Des Devel Ther8 citations - Level DNarrative ReviewEurope PMC
Metformin prevents the onset and progression of intervertebral disc degeneration: New insights and potential mechanisms (Review)
Narrative Review on Back Pain, Disc Degeneration, Type 2 Diabetes, published in Int J Mol Med (2024) — summary generated from the PubMed abstract.
- 2024
Int J Mol Med12 citations - Level DLaboratory StudyPubMed
Targeted CRISPR regulation of ZNF865 enhances stem cell cartilage deposition, tissue maturation rates, and mechanical properties in engineered intervertebral discs.
Laboratory Study on Back Pain, Disc Degeneration, published in Acta Biomater (2024) — summary generated from the PubMed abstract.
- 2024
Acta Biomater6 citations - Level DAnimal StudyPubMed
High impact works on stem cell transplantation in intervertebral disc degeneration.
Animal Study on Back Pain, Disc Degeneration, published in BMC Musculoskelet Disord (2024) — summary generated from the PubMed abstract.
- 2024
BMC Musculoskelet Disord1 citations - Level DNarrative ReviewPubMed
Nanoscale Treatment of Intervertebral Disc Degeneration: Mesenchymal Stem Cell Exosome Transplantation.
Narrative Review on Disc Degeneration, published in Curr Stem Cell Res Ther (2023) — summary generated from the PubMed abstract.
- 2023
Curr Stem Cell Res Ther15 citations - Level DAnimal StudyEurope PMC
Ion elemental-optimized layered double hydroxide nanoparticles promote chondrogenic differentiation and intervertebral disc regeneration of mesenchymal stem cells through focal adhesion signaling pathway
Animal Study on Back Pain, Disc Degeneration, published in Bioact Mater (2023) — summary generated from the PubMed abstract.
- 2023
Bioact Mater25 citations - Level DNarrative ReviewEurope PMC
Multiple nano-drug delivery systems for intervertebral disc degeneration: Current status and future perspectives
Narrative Review on Back Pain, Disc Degeneration, published in Bioact Mater (2023) — summary generated from the PubMed abstract.
- 2023
Bioact Mater79 citations - Level DLaboratory StudyPubMed
An international analysis of stem cell research in intervertebral disc degeneration.
Laboratory Study on Disc Degeneration, published in Stem Cell Res (2023) — summary generated from the PubMed abstract.
- 2023
Stem Cell Res3 citations - Level AMeta-analysisEurope PMC
Mesenchymal stem cells can improve discogenic pain in patients with intervertebral disc degeneration: a systematic review and meta-analysis
Meta-analysis with a reported sample of 245 on Disc Degeneration, published in Front Bioeng Biotechnol (2023) — summary generated from the PubMed abstract.
- 2023
- n = 245
Front Bioeng Biotechnol12 citations
In-depth reviewed studies (full Thai translation)
Evidence system- Level ARandomized Controlled Trial
Cell-based versus corticosteroid injections for knee pain in osteoarthritis: a randomized phase 3 trial
A multicentre randomized trial in 480 knee osteoarthritis patients comparing SVF, BMAC and umbilical cord MSCs against corticosteroid injection. At 12 months no cell product outperformed the steroid control.
- 2023
- United States
- n = 480
- Level AMeta-analysis
Intra-articular Injection of Autologous Adipose-Derived Stem Cells or Stromal Vascular Fractions: Are They Effective for Patients With Knee Osteoarthritis? A Systematic Review With Meta-analysis of Randomized Controlled Trials
Pooled five RCTs comparing ADSC/SVF injection with placebo or hyaluronic acid, finding significant pain and function improvement at 6 and 12 months.
- 2023
- South Korea
- Level AMeta-analysis
Rapid-acting pain relief in knee osteoarthritis: autologous-cultured adipose-derived mesenchymal stem cells outperform stromal vascular fraction: a systematic review and meta-analysis
Analysed 31 studies with 1,406 patients: cultured ADMSCs reduced pain from month 3, whereas SVF reached significance only at 12 months.
- 2024
- South Korea
- n = 1406